Breadcrumb
- Home
- Illnesses & Conditions
- Cancer
- Endometrial (Uterine) Cancer
Content Map Terms
Illnesses & Conditions Categories
-
Allergies
- Allergy to Natural Rubber (Latex)
- Jellyfish Stings: Allergic Reaction
- Allergies: Should I Take Allergy Shots?
- Non-Allergic Rhinitis
- Allergic Reaction
- Allergies
- Allergy Shots for Allergic Rhinitis
- Allergies: Rush Immunotherapy
- Over-the-Counter Medicines for Allergies
- Allergic Rhinitis
- Types of Allergens
- Allergies: Avoiding Indoor Triggers
- Allergies: Avoiding Outdoor Triggers
- Controlling Dust, Dust Mites, and Other Allergens in Your Home
- Controlling Pet Allergens
- Allergies to Insect Stings
- Allergies: Should I Take Shots for Insect Sting Allergies?
- Immunotherapy for Allergies to Insect Stings
- Types of Allergic Rhinitis
- Allergic Reaction to Tattoo Dye
- Drug Allergies
- Penicillin Allergy
- Hay Fever and Other Seasonal Allergies
- Allergies: Giving Yourself an Epinephrine Shot
-
Arthritis and Osteoporosis
- Rheumatoid Arthritis: Finger and Hand Surgeries
- Rheumatoid Arthritis: Classification Criteria
- Rheumatoid Arthritis: Systemic Symptoms
- Comparing Rheumatoid Arthritis and Osteoarthritis
- Rheumatoid Arthritis: Neck Symptoms
- Osteoporosis in Men
- Psoriatic Arthritis
- Arthritis: Shots for Knee Pain
- Complementary Medicine for Arthritis
- Steve's Story: Coping With Arthritis
- Bev's Story: Coping With Arthritis
- Quick Tips: Modifying Your Home and Work Area When You Have Arthritis
- Coping With Osteoarthritis
- Arthritis: Should I Have Shoulder Replacement Surgery?
- Juvenile Idiopathic Arthritis: Stretching and Strengthening Exercises
- Juvenile Idiopathic Arthritis
- Capsaicin for Osteoarthritis
- Small Joint Surgery for Osteoarthritis
- Osteoarthritis: Heat and Cold Therapy
- Modifying Activities for Osteoarthritis
- Osteoarthritis
- Gout
- Rheumatoid Arthritis
- Juvenile Idiopathic Arthritis: Inflammatory Eye Disease
- Juvenile Idiopathic Arthritis: Range-of-Motion Exercises
- Juvenile Idiopathic Arthritis: Deciding About Total Joint Replacement
- Complications of Osteoarthritis
- Arthritis: Managing Rheumatoid Arthritis
- Arthritis: Should I Have Knee Replacement Surgery?
- Arthritis: Should I Have Hip Replacement Surgery?
- Juvenile Idiopathic Arthritis: Pain Management
- Osteoporosis Risk in Younger Women
- Osteoporosis Screening
-
Asthma
- Asthma: Peak Expiratory Flow and Personal Best
- Asthma and Wheezing
- Asthma: Using an Asthma Action Plan
- Asthma: Measuring Peak Flow
- Asthma: Identifying Your Triggers
- Steroid Medicine for Asthma: Myths and Facts
- Asthma
- Inhaled corticosteroids for asthma
- Inhaled quick-relief medicines for asthma
- Classification of Asthma
- Challenge Tests for Asthma
- Asthma's Impact on Your Child's Life
- Asthma Action Plan: Yellow Zone
- Asthma Triggers
- Asthma Action Plan: Red Zone
- Asthma and GERD
- Occupational Asthma
- Asthma Attack
- Asthma: Symptoms of Difficulty Breathing
- Exercise-Induced Asthma
- Asthma Treatment Goals
- Asthma: Overcoming Obstacles to Taking Medicines
- Asthma in Older Adults: Managing Treatment
- Asthma: Controlling Cockroaches
- Asthma: Educating Yourself and Your Child
- Allergy Shots for Asthma
- Asthma: Taking Charge of Your Asthma
- Monitoring Asthma Treatment
- Omalizumab for Asthma
- Asthma: Ways to Take Inhaled Medicines
- Asthma: Overuse of Quick-Relief Medicines
- Asthma Diary
- Asthma Diary Template
- Asthma Action Plan
- Assessing Your Asthma Knowledge
- My Asthma Action Plan
-
Bowel and Gastrointestinal Conditions
- Abdominal Fullness or Bloating
- Irritable Bowel Syndrome: Criteria for Diagnosis
- Gastritis
- Gas, Bloating, and Burping
- Irritable Bowel Syndrome (IBS)
- Constipation: Keeping Your Bowels Healthy
- Rectal Problems
- Mild, Moderate, or Severe Diarrhea
- Torn or Detached Nail
- Chronic Constipation
- Gas (Flatus)
- Dyspepsia
- Diverticulosis
- Bowel Obstruction
- Anal Fissure
- Bowel Disease: Caring for Your Ostomy
- Anal Fistulas and Crohn's Disease
-
Cancer
- Lung Cancer and Other Lung Problems From Smoking
- Skin Cancer, Non-Melanoma
- Radiation Therapy for Non-Melanoma Skin Cancer
- Colorectal Cancer Test Recommendations
- Breast Cancer Screening: When Should I Start Having Mammograms?
- Lifestyle Changes That May Help Prevent Cancer
- Choosing a Prosthesis After Breast Cancer Surgery
- Hormone Treatment for Breast Cancer
- Cancer Staging and Grading
- Pancreatic Cancer
- Kidney (Renal Cell) Cancer
- Cancer Support: Managing Stress
- Cancer Support: When Your Cancer Comes Back or Gets Worse
- Cancer Support: Dealing With Emotions and Fears
- Cancer Support: Finding Out That You Have Cancer
- Cancer Support: Being an Active Patient
- Cancer Support: Coping With Cancer Treatments
- Cancer Support: Life After Treatment
- Cancer Support: Family, Friends, and Relationships
- Reducing Cancer Risk When You Are BRCA-Positive
- Anal Cancer
- Prostate Cancer: Should I Choose Active Surveillance?
- Lung Cancer Screening
- Basal Cell Skin Cancer: Should I Have Surgery or Use Medicated Cream?
- Tumour Markers
- Does Aspirin Prevent Cancer?
- Cancer
- Lung Cancer
- Oral Cancer
- Colorectal Cancer
- Metastatic Melanoma
- Radiation Treatment for Cancer
- Skin Cancer, Melanoma
- Cervical Cancer Screening
- Hepatitis B and C: Risk of Liver Cancer
- Inflammatory Bowel Disease and Cancer Risk
- Radiation Therapy for Prostate Cancer
- Prostate Cancer
- Cancer: Home Treatment for Mouth Sores
- Skin Cancer Screening
- Breast Cancer: Should I Have Breast Reconstruction After a Mastectomy?
- Prostate Cancer: Should I Have Radiation or Surgery for Localized Prostate Cancer?
- Prostate Cancer Screening
- Side Effects of Chemotherapy
- Breast Cancer: Lymph Node Surgery for Staging Cancer
- Endometrial (Uterine) Cancer
- Cryosurgery for Prostate Cancer
- Breast Cancer
- Cancer: Home Treatment for Nausea or Vomiting
- Cancer: Home Treatment for Pain
- Cancer: Home Treatment for Diarrhea
- Cancer: Home Treatment for Constipation
- Breast Cancer Types
- Cancer: Home Treatment for Sleep Problems
- Cancer: Home Treatment for Fatigue
- Hair Loss From Cancer Treatment
- Body Image After Cancer Treatment
- Breast Cancer: Should I Have Breast-Conserving Surgery or a Mastectomy for Early-Stage Cancer?
- Breast Cancer, Metastatic or Recurrent
- Cancer Pain
- Leukemia
- Colorectal Cancer, Metastatic or Recurrent
- Thyroid Cancer
- Types of Thyroid Cancer
- Radiation Therapy for Cancer Pain
- Breast Cancer in Men (Male Breast Cancer)
- Breast Cancer Screening
- Breast Cancer: Should I Have Chemotherapy for Early-Stage Breast Cancer?
- Asbestos and Lung Cancer
- Cervical Cancer
- Ovarian Cancer
- Colon Cancer Genetic Testing
- Testicular Cancer Screening
- Skin Cancer: Protecting Your Skin
- Non-Melanoma Skin Cancer: Comparing Treatments
- Bladder Cancer
- Prostate Cancer, Advanced or Metastatic
- Active Surveillance for Prostate Cancer
- Urinary Problems and Prostate Cancer
- Cancer: Controlling Cancer Pain
- Heat and Cold Treatment for Cancer Pain
- Testicular Cancer
- Testicular Cancer: Which Treatment Should I Have for Stage I Non-Seminoma Testicular Cancer After My Surgery?
- Testicular Cancer: Which Treatment Should I Have for Stage I Seminoma Testicular Cancer After My Surgery?
- Cancer: Controlling Nausea and Vomiting From Chemotherapy
- Lymphedema: Managing Lymphedema
- Breast Cancer Risk: Should I Have a BRCA Gene Test?
- Inflammatory Breast Cancer
- Ovarian Cancer: Should I Have My Ovaries Removed to Prevent Ovarian Cancer?
- Family History and the Risk for Breast or Ovarian Cancer
- Breast Cancer: What Should I Do if I'm at High Risk?
-
Cold and Flu
- Difference Between Influenza (Flu) and a Cold
- Colds and Flu
- Influenza (Flu) Complications
- Flu Vaccine Myths
- Influenza (Seasonal Flu)
- Whooping Cough (Pertussis)
- Productive Coughs
- Dry Coughs
- Influenza (Flu): Should I Take Antiviral Medicine?
- Flu Vaccines: Should I Get a Flu Vaccine?
- Relieving A Cough
- Colds
-
COPD
- Cal's Story: Learning to Exercise When You have COPD
- Conserving Energy When You Have COPD or Other Chronic Conditions
- Nebulizer for COPD Treatment
- COPD Action Plan
- COPD: Help for Caregivers
- COPD: Keeping Your Diet Healthy
- COPD: Using Exercise to Feel Better
- COPD
- COPD Flare-Ups
- Bullectomy for COPD
- COPD and Alpha-1 Antitrypsin (AAT) Deficiency
- COPD and Sex
- Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease (COPD)
- COPD
- Oxygen Treatment for Chronic Obstructive Pulmonary Disease (COPD)
- COPD: Avoiding Weight Loss
- COPD: Avoiding Your Triggers
-
Dementia
- Alzheimer's or Other Dementia: Should I Move My Relative Into Long-Term Care?
- Alzheimer's and Other Dementias: Coping With Sundowning
- Dementia: Assessing Pain
- Medical History and Physical Examination for Dementia or Alzheimer's Disease
- Alzheimer's and Other Dementias: Making the Most of Remaining Abilities
- Dementia: Helping a Person Avoid Confusion
- Alzheimer's and Other Dementias: Maintaining Good Nutrition
- Dementia: Tips for Communicating
- Agitation and Dementia
- Dementia: Bladder and Bowel Problems
- Dementia: Support for Caregivers
- Dementia: Legal Issues
- Dementia: Understanding Behaviour Changes
- Dementia: Medicines to Treat Behaviour Changes
- Dementia
- Mild Cognitive Impairment and Dementia
-
Diabetes
- Diabetes: Blood Sugar Levels
- Diabetes: Counting Carbs if You Don't Use Insulin
- Diabetes: Coping With Your Feelings About Your Diet
- Diabetes: Tracking My Feelings
- Diabetes: Taking Care of Your Feet
- Diabetes: Care of Blood Sugar Test Supplies
- Diabetes: Checking Your Blood Sugar
- Diabetes: Checking Your Feet
- Diabetes: Steps for Foot-Washing
- Diabetes: Protecting Your Feet
- Diabetes: Dealing With Low Blood Sugar From Medicines
- Diabetes: Dealing With Low Blood Sugar From Insulin
- Diabetes: How to Give Glucagon
- Low Blood Sugar Level Record
- Symptoms of Low Blood Sugar
- Diabetes: Preventing High Blood Sugar Emergencies
- Diabetic Ketoacidosis (DKA)
- High Blood Sugar Level Record
- Symptoms of High Blood Sugar
- Diabetes: Using a Plate Format to Plan Meals
- Diabetes: Giving Yourself an Insulin Shot
- Diabetes: Eating Low-Glycemic Foods
- Diabetes and Alcohol
- Continuous Glucose Monitoring
- Quick Tips: Diabetes and Shift Work
- Diabetes: How to Prepare for a Colonoscopy
- Type 2 Diabetes: Can You Cure It?
- Diabetes, Type 2: Should I Take Insulin?
- Prediabetes: Which Treatment Should I Use to Prevent Type 2 Diabetes?
- Diabetes: Making Medical Decisions as Your Health Changes
- Diabetes Care Plan
- Diabetes: Caregiving for an Older Adult
- Quick Tips: Smart Snacking When You Have Diabetes
- Testing Tips From a Diabetes Educator
- Gloria's Story: Adding Activity to Help Control Blood Sugar
- Andy's Story: Finding Your Own Routine When You Have Diabetes
- Jerry's Story: Take Prediabetes Seriously
- Linda's Story: Getting Active When You Have Prediabetes
- Diabetes
- Tips for Exercising Safely When You Have Diabetes
- Diabetes: Travel Tips
- Type 2 Diabetes
- Type 1 Diabetes
- Care of Your Skin When You Have Diabetes
- Care of Your Teeth and Gums When You Have Diabetes
- Non-insulin medicines for type 2 diabetes
- Metformin for diabetes
- Hypoglycemia (Low Blood Sugar) in People Without Diabetes
- Diabetic Retinopathy
- Laser Photocoagulation for Diabetic Retinopathy
- Diabetic Neuropathy
- Diabetic Focal Neuropathy
- Diabetic Neuropathy: Exercising Safely
- Diabetic Autonomic Neuropathy
- Criteria for Diagnosing Diabetes
- Diabetes-Related High and Low Blood Sugar Levels
- Diabetic Nephropathy
- Diabetes: Counting Carbs if You Use Insulin
- Diabetes: Cholesterol Levels
- Diabetes and Infections
- Diabetes: Tests to Watch for Complications
- Diabetes: Differences Between Type 1 and 2
- Diabetes Complications
- How Diabetes Causes Blindness
- How Diabetes Causes Foot Problems
- Reading Food Labels When You Have Diabetes
- Eating Out When You Have Diabetes
- Breastfeeding When You Have Diabetes
- Diabetes: Staying Motivated
- Sick-Day Guidelines for People With Diabetes
- Diabetes: Amputation for Foot Problems
- Prediabetes
- Prediabetes: Exercise Tips
- Type 2 Diabetes: Screening for Adults
- Diabetes: Should I Get an Insulin Pump?
- Diabetes: Living With an Insulin Pump
- Form for Carbohydrate Counting
-
Disease and Disease Prevention
- Diseases and Conditions
- Osgood-Schlatter Disease
- Needle Aponeurotomy for Dupuytren's Disease
- Mitochondrial Diseases
- Disease and Injury Prevention
- Alzheimer's Disease
- Root Planing and Scaling for Gum Disease
- Kawasaki Disease
- Tay-Sachs Disease
- Von Willebrand's Disease
- Hirschsprung's Disease
- Complications of Paget's Disease
- Paget's Disease of Bone
- Celiac Disease
- Peptic Ulcer Disease
- Ménière's Disease
- Pelvic Inflammatory Disease: Tubo-Ovarian Abscess
- Pelvic Inflammatory Disease
- Addison's Disease
- Misdiagnosis of Lyme Disease
- Lyme Disease
- Parkinson's Disease and Freezing
- Parkinson's Disease: Other Symptoms
- Parkinson's Disease: Modifying Your Activities and Your Home
- Parkinson's Disease and Tremors
- Parkinson's Disease and Speech Problems
- Parkinson's Disease
- Disease-modifying antirheumatic drugs (DMARDs)
- Parkinson's Disease: Movement Problems From Levodopa
- Mad Cow Disease
- Handwashing
- Peyronie's Disease
- Stages of Lyme Disease
- Osteotomy and Paget's Disease
- Dupuytren's Disease
- Crohn's Disease
- Crohn's Disease: Problems Outside the Digestive Tract
- Pilonidal Disease
- Acquired Von Willebrand's Disease
-
Down Syndrome, Autism and Developmental Delays
- Autism
- Down Syndrome: Helping Your Child Eat Independently
- Down Syndrome: Grooming and Hygiene
- Down Syndrome: Helping Your Child Learn to Walk and Use Other Motor Skills
- Down Syndrome: Helping Your Child Learn to Communicate
- Down Syndrome
- Dyslexia
- Conditions Related to Dyslexia
- Autism: Behavioural Training and Management
- Autism: Support and Training for the Family
- Unproven Treatments for Autism
- Caring for Adults With Autism
- Down Syndrome: Helping Your Child Avoid Social Problems
- Down Syndrome: Training and Therapy for Young People
- Down Syndrome: Helping Your Child Dress Independently
- Down Syndrome, Ages Birth to 1 Month
- Down Syndrome, Ages 1 Month to 1 Year
- Down Syndrome, Ages 1 to 5
- Down Syndrome, Ages 5 to 13
- Down Syndrome, Ages 13 to 21
- Eating Disorders
-
Epilepsy
- Absence Epilepsy
- Juvenile Myoclonic Epilepsy
- Temporal Lobe Epilepsy
- Focal Epilepsy
- Epilepsy: Simple Partial Seizures
- Epilepsy
- Epilepsy and Driving
- Epilepsy: Generalized Seizures
- Epilepsy: Generalized Tonic-Clonic Seizures
- Epilepsy: Myoclonic Seizures
- Epilepsy: Atonic Seizures
- Epilepsy: Tonic Seizures
- Epilepsy: Complex Partial Seizures
- Epilepsy Medicine Therapy Failure
- Stopping Medicine for Epilepsy
- Questions About Medicines for Epilepsy
- Epilepsy: Taking Your Medicines Properly
-
Fatigue and Sleep
- Sleep Apnea: Should I Have a Sleep Study?
- Sleep and Your Health
- Quick Tips: Making the Best of Shift Work
- Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Managing Your Energy
- Sleeping Better
- Sleep Problems
- Doxepin (Sleep) - Oral
- Improving Sleep When You Have Chronic Pain
- Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
- Chronic Fatigue: Changing Your Schedule
- Chronic Fatigue: Getting Support
- Snoring and Obstructive Sleep Apnea
- Coping With Changing Sleep Patterns as You Get Older
- Stages of Sleep
- Sleep Apnea: Fibre-Optic Pharyngoscopy
- Sleep Apnea: Oral Devices
- Continuous Positive Airway Pressure (CPAP) Therapy for Obstructive Sleep Apnea
- Sleep Apnea
- Sleep Problems, Age 12 and Older
- Stages of Sleep Apnea
- Sleep Journal
- Shift Work Sleep Disorder
- Snoring
- Sleep Problems: Dealing With Jet Lag
- Insomnia
- Sleep and Your Body Clock
- Weakness and Fatigue
- Insomnia: Improving Your Sleep
-
Heart Health and Stroke
- Peripheral Arterial Disease of the Legs
- Bradycardia (Slow Heart Rate)
- Types of Bradycardia
- Cardiac Device Monitoring
- Angioplasty for Peripheral Arterial Disease of the Legs
- Isolated Systolic High Blood Pressure
- Atrial Fibrillation: Should I Try Electrical Cardioversion?
- Change in Heartbeat
- Deep Vein Thrombosis
- Fast Heart Rate
- Heart Failure: Symptom Record
- Heart Failure: Compensation by the Heart and Body
- Heart Failure: Taking Medicines Properly
- Heart Failure: Watching Your Fluids
- Heart Failure: Avoiding Triggers for Sudden Heart Failure
- Heart Failure: Activity and Exercise
- Heart Tests: When Do You Need Them?
- Low Blood Pressure (Hypotension)
- Cardiac Arrest
- Heart Failure Daily Action Plan
- Premature Ventricular Contractions (PVCs)
- Heart Rate Problems: Should I Get a Pacemaker?
- Heart Rhythm Problems: Should I Get an Implantable Cardioverter-Defibrillator (ICD)?
- What to Do if Your Cardiac Device Is Recalled
- Venous Insufficiency
- Carotid Artery Stenting
- ICD: Living Well With It
- Diabetes: Lower Your Risk for Heart Attack and Stroke
- Pacemaker for Heart Failure (Cardiac Resynchronization Therapy)
- Heart Attack: How to Prevent Another One
- Stroke: How to Prevent Another One
- Sex and Your Heart
- Supraventricular Tachycardia: Should I Have Catheter Ablation?
- Carotid Artery Disease
- Giant Cell Arteritis
- High Blood Pressure: Over-the-Counter Medicines to Avoid
- Postural Orthostatic Tachycardia Syndrome (POTS)
- Leg Aneurysm
- Pulmonary Hypertension
- Left Ventricular Hypertrophy (LVH)
- Heart Failure: Checking Your Weight
- Alan's Story: Coping With Change After a Heart Attack
- Coronary Artery Disease: Prevention Myths
- Quick Tips: Taking Charge of Your Angina
- Heart and Circulation
- High Blood Pressure
- Heartburn
- Angioplasty for Coronary Artery Disease
- Coronary Artery Disease
- Implantable Cardioverter-Defibrillator (ICD)
- Aortic Valve Regurgitation
- Aortic Valve Stenosis
- Secondary High Blood Pressure
- Hemorrhagic Stroke
- Stroke: Common Disabilities
- Self-Care After a Stroke
- Stroke: Dealing With Depression
- Stroke: Getting Dressed
- Stroke: Speech and Language Problems
- Stroke: Bladder and Bowel Problems
- Stroke: Preventing Injury in Affected Limbs
- After a Stroke: Helping Your Family Adjust
- Stroke: Behaviour Changes
- Stroke: Changes in Emotions
- Stroke: Perception Changes
- Stroke: Problems With Ignoring the Affected Side
- Stroke: Memory Tips
- Stroke: Your Rehabilitation Team
- Stroke
- Transient Ischemic Attack (TIA)
- Cardiac Rehabilitation: Lifestyle Changes
- Cardiac Rehabilitation: Hospital Program
- Cardiac Rehabilitation: Home Program
- Cardiac Rehabilitation: Outpatient Program
- Cardiac Rehabilitation: Maintenance Program
- Congenital Heart Defects
- Congenital Heart Defects: Caring for Your Child
- Coronary Artery Disease: Should I Have an Angiogram?
- Triggers of Sudden Heart Failure
- Classification of Heart Failure
- Heart Failure: Tips for Easier Breathing
- Heart Failure: Avoiding Colds and Flu
- Heart Failure
- Helping Someone During a Panic Attack
- Aortic Aneurysm
- High Blood Pressure
- Coronary Artery Disease: Family History
- Angina
- Using Nitroglycerin for Angina
- Heartburn: Changing Your Eating Habits
- Angiotensin II receptor blockers (ARBs)
- Beta-blockers
- Heart Rhythm Problems: Diary of Symptoms
- Vagal Manoeuvres for Supraventricular Tachycardia (SVT)
- Electrical Cardioversion (Defibrillation) for a Fast Heart Rate
- Catheter Ablation for a Fast Heart Rate
- Supraventricular Tachycardia
- Home Blood Pressure Log
- Blood Pressure Screening
- Heart Block
- Electrical System of the Heart
- Heart Rhythm Problems and Driving
- Heart Rhythm Problems: Symptoms
- Resuming Sexual Activity After a Heart Attack
- Risk Factors for Coronary Artery Disease
- Pacemaker for Bradycardia
- SPECT Image of the Heart
- Heart Attack and Stroke in Women: Reducing Your Risk
- Ventricular Tachycardia
- Aspirin to Prevent Heart Attack and Stroke
- Temporal Artery Biopsy
- Emergency First Aid for Heatstroke
- Heartburn Symptom Record
- Heart Attack and Unstable Angina
- Congenital Heart Defects in Adults
- Monitoring and Medicines for Heart Failure
- Ventricular Assist Device (VAD) for Heart Failure
- Cardiac Output
- Heart Failure Symptoms
- Heart Failure: Less Common Symptoms
- Heart Failure With Reduced Ejection Fraction (Systolic Heart Failure)
- Heart Failure With Preserved Ejection Fraction (Diastolic Heart Failure)
- High-Output Heart Failure
- Right-Sided Heart Failure
- Heart Failure Complications
- How the Heart Works
- Coronary Arteries and Heart Function
- Heart Failure Types
- Enjoying Life When You Have Heart Failure
- Heart Failure: Tips for Caregivers
- Medicines to Prevent Abnormal Heart Rhythm in Heart Failure
- Cardiac Cachexia
- Heart Failure Stages
- Cardiac Rehabilitation Team
- Cardiac Rehabilitation: Emotional Health Benefits
- Ischemia
- Coronary Artery Disease: Roles of Different Doctors
- Coronary Artery Disease: Helping a Loved One
- Manage Stress for Your Heart
- Intermittent Claudication
- Peripheral Arterial Disease: Pulse and Blood Pressure Measurement
- Heart Failure and Sexual Activity
- Joan's Story: Coping With Depression and Anxiety From Heart Failure
- Rheumatic Fever and the Heart
- Heart Valve Problems: Should I Choose a Mechanical Valve or Tissue Valve to Replace My Heart Valve?
- Acute Coronary Syndrome
- Aspirin: Should I Take Daily Aspirin to Prevent a Heart Attack or Stroke?
- Heart Failure: Should I Get a Pacemaker ?
- Heart Failure: Should I Get an Implantable Cardioverter-Defibrillator (ICD)?
- Heart Valve Disease
- Myxoma Tumours of the Heart
- Aortic Dissection
- Heart Attack and Stroke Risk Screening
- High Blood Pressure: Checking Your Blood Pressure at Home
- Hypertensive Emergency
- Stroke Rehabilitation
- Treatment for Stroke-Related Spasticity
- Driving a Car After a Stroke
- Heart Failure: Avoiding Medicines That Make Symptoms Worse
- Stroke Recovery: Coping With Eating Problems
- Heart Murmur
- High Blood Pressure: Should I Take Medicine?
- Coronary Artery Disease: Should I Have Angioplasty for Stable Angina?
- Tyrell's Story: Taking Pills for High Blood Pressure
- Stroke Prevention: Should I Have a Carotid Artery Procedure?
- Atrial Fibrillation: Which Anticoagulant Should I Take to Prevent Stroke?
- Stroke: Should I Move My Loved One Into Long-Term Care?
- Atrial Fibrillation: Should I Take an Anticoagulant to Prevent Stroke?
- Smoking and Coronary Artery Disease
-
Hepatitis
- Hepatitis C: Your Risk for Cirrhosis
- Hepatitis E
- Hepatitis B Immune Globulin - Injection
- Heparin - Injection
- Fulminant Hepatitis
- Protect Yourself From Hepatitis A When Travelling
- Hepatitis A
- Viral Hepatitis
- Hepatitis C
- Hepatitis D
- Hepatitis B: How to Avoid Spreading the Virus
- Hepatitis B
- Hepatitis Panel
- Hepatitis B Treatment Recommendations
- Hepatitis B: Should I Be Tested?
-
HIV
- HIV Infection
- HIV Viral Load
- HIV: Stages of Infection
- Ways HIV Cannot Be Spread
- HIV and Exercise
- HIV: Giving Support
- HIV: Tips for Caregivers to Avoid Infection
- HIV: Preventing Other Infections When You Have HIV
- HIV Home Care
- Antiretroviral medicines for HIV
- Resistance to HIV Medicines
- HIV: Preventing Infections
- HIV: Antiretroviral Therapy (ART)
- Opportunistic Infections in HIV
- HIV: Taking Antiretroviral Drugs
- HIV: Non-Progressors and HIV-Resistant People
- HIV Screening
- HIV and Weight Loss
- HIV and Fatigue
-
Infectious Diseases
- Anthrax
- Avian Influenza
- Avoiding Infections in the Hospital
- Bacterial Infections of the Spine
- Bites and Stings: Flu-Like Symptoms
- Boric Acid for Vaginal Yeast Infection
- Caregiving: Reducing Germs and Infection in the Home
- Central Venous Catheter: Flushing
- Chickenpox (Varicella)
- Chickenpox: Preventing Skin Infections
- Chikungunya Fever
- Complicated Urinary Tract Infections
- Complications of Ear Infections
- Cranberry Juice and Urinary Tract Infections
- Dengue Fever
- Ear Infection: Should I Give My Child Antibiotics?
- Ear Infections
- Ebola or Marburg Virus Infection
- Ebola Virus Disease
- Enterovirus D68 (EV-D68)
- Fever or Chills, Age 11 and Younger
- Fever or Chills, Age 12 and Older
- Fever Seizures
- Fever Temperatures: Accuracy and Comparison
- Feverfew for Migraines
- Fifth Disease
- Flu: Signs of Bacterial Infection
- Fungal Nail Infections
- Giardiasis
- Hand-Foot-and-Mouth Disease
- Kissing Bugs
- Measles (Rubeola)
- Middle East Respiratory Syndrome (MERS)
- Molluscum Contagiosum
- Monkeypox
- Mononucleosis (Mono)
- Mononucleosis Complications
- Mumps
- Nail Infection: Should I Take Antifungal Pills?
- Neutropenia: Preventing Infections
- Non-Surgical Nail Removal for Fungal Nail Infections
- Noroviruses
- Pleurisy
- Pneumonia
- Preventing Tetanus Infections
- Pseudomonas Infection
- Recurrent Ear Infections and Persistent Effusion
- Recurrent Vaginal Yeast Infections
- Respiratory Syncytial Virus (RSV) Infection
- Rotavirus
- Rubella (German Measles)
- Scarlet Fever
- Sexually Transmitted Infections
- Sexually Transmitted Infections: Genital Examination for Men
- Sexually Transmitted Infections: Symptoms in Women
- Sexually Transmitted Infections: Treatment
- Shingles
- Smallpox
- Sore Throat and Other Throat Problems
- Staph Infection
- Strep Throat
- Symptoms of Pelvic Infection
- Thrush
- Tick Bites: Flu-Like Symptoms
- Tinea Versicolor
- Tuberculosis (TB)
- Tuberculosis Screening
- Urinary Tract Infections (UTIs) in Older Adults
- Vaginal Yeast Infection: Should I Treat It Myself?
- Vaginal Yeast Infections
- Valley Fever
- West Nile Virus
- Zika Virus
- Informed Health Decisions
-
Injuries
- Trapped Finger, Toe, or Limb
- Blister Care
- Exercises for Heel Pain or Tightness
- Broken Toe
- Broken Nose (Nasal Fracture)
- Preventing Blisters
- Hip Fracture
- Medial Collateral Ligament (MCL) Injury
- Pressure Injuries From Scuba Diving
- Pressure Injuries: Stages
- Pressure Injuries: Prevention and Treatment
- Calf Muscle Injury
- Avulsion Fracture
- Lateral Collateral Ligament (LCL) Injury
- Posterior Cruciate Ligament (PCL) Injury
- Frozen or Stuck Tongue or Other Body Part
- Fifth Metatarsal Jones Fracture
- Animal and Human Bites
- Blisters
- Burns and Electric Shock
- Choking Rescue Procedure: Heimlich Manoeuvre
- Cold Temperature Exposure
- Cuts
- Ear Problems and Injuries, Age 11 and Younger
- Elbow Injuries
- Elbow Problems, Non-Injury
- Facial Injuries
- Facial Problems, Non-Injury
- Fish Hook Injuries
- Toe, Foot, and Ankle Injuries
- Groin Problems and Injuries
- Finger, Hand, and Wrist Injuries
- Anterior Cruciate Ligament (ACL) Injuries
- Safe Hand and Wrist Movements
- Physical Rehabilitation for ACL Injuries
- Marine Stings and Scrapes
- Mouth Problems, Non-Injury
- Nail Problems and Injuries
- Puncture Wounds
- Shoulder Problems and Injuries
- Removing Splinters
- Swallowed Button Disc Battery, Magnet, or Object With Lead
- Object Stuck in the Throat
- How a Scrape Heals
- Removing an Object From a Wound
- Types of Chest Injuries
- Injury to the Tailbone (Coccyx)
- First Aid for a Spinal Injury
- Body Mechanics
- Scrapes
- Swallowed or Inhaled Objects
- Swelling
- Overuse Injuries
- Meniscus Tear
- Razor Bumps
- Ankle Sprain
- Sprained Ankle: Using a Compression Wrap
- High-Pressure Injection Wounds
- Patellar Dislocation
- Hamstring Muscles
- Plica in the Knee
- Spondylolysis and Spondylolisthesis
- Pressure Injuries
- Heat After an Injury
- Concussion
- Navicular (Scaphoid) Fracture of the Wrist
- Cold Exposure: What Increases Your Risk of Injury?
- Broken Collarbone (Clavicle)
- Shoulder Separation
- Frozen Shoulder
- Preventing ACL Injuries
- Living With a Spinal Cord Injury
- Classification of Spinal Cord Injuries
- Tendon Injury (Tendinopathy)
- Shin Splints
- Muscle Cramps
- Whiplash
- Fractured Rib
-
Joints and Spinal Conditions
- Osteochondritis Dissecans of a Joint
- Back to Work?
- Moving From Sitting to Standing
- Golfer's Elbow
- Bones, Joints, and Muscles
- Hip Injuries, Age 11 and Younger
- Hip Injuries, Age 12 and Older
- Hip Problems, Age 12 and Older
- Rotator Cuff Disorders
- Osteoporosis
- Spina Bifida
- Temporomandibular Disorders: Having Good Body Mechanics
- Temporomandibular Disorders (TMD)
- Tennis Elbow
- Debridement for Rotator Cuff Disorders
- Spinal Curves in Scoliosis
- Spondyloarthropathies
- Knee Problems and Injuries
- Posture: Standing and Walking
- Osteoporosis Risk Factors
- Bruxism and Temporomandibular Disorders
- Patellar Subluxation
- Steroid-Induced Osteoporosis
- Cervical Spinal Stenosis
- Lumbar Spinal Stenosis
- Spasticity
- Scoliosis In Adults
- Acute Flaccid Myelitis
- Spinal Cord Injury: Assisted Cough
- Spinal Cord Injury: Your Rehabilitation Team
- Spinal Cord Injury: Talking With Your Partner About Sex
- Mobility After a Spinal Cord Injury
- Spinal Cord Injury: Adapting Your Home
- Spinal Cord Injury: Safe Transfers To or From a Wheelchair
- Spinal Cord Injury: Autonomic Dysreflexia
- Back Problems and Injuries
- Proper Sitting for a Healthy Back
- Brace (Orthotic) Treatment for Scoliosis
- Proper Back Posture (Neutral Spine)
- Severity of Back Injuries
- Back Problems: Proper Lifting
- Degenerative Disc Disease
-
Kidneys
- Acute Kidney Injury Versus Chronic Kidney Disease
- Nephrotic Syndrome
- Uremia
- Kidney Stones: Should I Have Lithotripsy to Break Up the Stone?
- Chronic Kidney Disease
- Kidney Failure: When Should I Start Dialysis?
- Kidney Failure: Should I Start Dialysis?
- Anemia of Chronic Kidney Disease
- End-Stage Kidney Failure
- Tolvaptan (Inherited Kidney Disease) - Oral
- Types of Kidney Stones
- Extracorporeal Shock Wave Lithotripsy (ESWL) for Kidney Stones
- Percutaneous Nephrolithotomy or Nephrolithotripsy for Kidney Stones
- Kidney Stones
- Advance Care Planning: Should I Stop Kidney Dialysis?
- Kidney Disease: Medicines to Avoid
- Stages of Chronic Kidney Disease
- Medicines That Can Cause Acute Kidney Injury
- Donating a Kidney
- Kidney Stones: Medicines That Increase Your Risk
-
Lung and Respiratory Conditions
- Breathing Problems: Using a Metered-Dose Inhaler
- Acute Respiratory Distress Syndrome (ARDS)
- Bronchiectasis
- Chest Problems
- Sildenafil 20 Mg (Lungs) - Oral
- Tadalafil (Lungs) - Oral
- Tests for Lung Infections
- COPD: Lung Volume Reduction Surgery
- Acute Bronchitis
- Respiratory Problems, Age 11 and Younger
- Respiratory Problems, Age 12 and Older
- Breathing Smoke or Fumes
- Pulmonary (Lung) Nodules
- Severe Acute Respiratory Syndrome (SARS)
- COPD's Effect on the Lungs
- Black Lung Disease
- Oral Breathing Devices for Snoring
- Spinal Cord Injury: Breathing Practice
- Breathing Problems: Using a Dry Powder Inhaler
- COPD: Clearing Your Lungs
- Collapsed Lung (Pneumothorax)
- Interactive Tool: Should I Consider Surgery for My Low Back Problem?
- COPD: Learning to Breathe Easier
- Lung Function in COPD
- COPD: Handling a Flare-Up
- Sarah's Story: Dealing With the Emotions From COPD
- Fran's Story: Finding Support When You Have COPD
-
Multiple Sclerosis
- Multiple Sclerosis: Alternative Treatments
- Multiple Sclerosis: Modifying Your Home
- Multiple Sclerosis: Bladder Problems
- Multiple Sclerosis (MS)
- Types of Multiple Sclerosis
- Multiple Sclerosis Progression
- Multiple Sclerosis: MRI Results
- Multiple Sclerosis: Mental and Emotional Problems
- Multiple Sclerosis: Questions About What to Expect
- Rehabilitation Programs for Multiple Sclerosis
- Obesity
-
Rehabilitation and Exercise
- Breathing Exercises: Using a Manual Incentive Spirometer
- Sensual Exercises for Erection Problems
- Breastfeeding: Exercise and Weight Loss
- Jaw Problems: Exercise and Relaxation
- Exercises for Arm and Wrist
- Kegel Exercises
- Tennis Elbow: Stretches and Strengthening Exercises
- Cardiac Rehabilitation: Exercise
- Neck Exercises
- Stress Management: Imagery Exercises
- Sprained Ankle: Rehabilitation Exercises
- Plantar Fasciitis: Exercises to Relieve Pain
- Cardiac Rehabilitation: Medicine and Exercise
- Cardiac Rehabilitation: Monitoring Your Body's Response to Exercise
- Rotator Cuff Problems: Exercises You Can Do at Home
- Stress Management: Breathing Exercises
- ACL Injury: Exercises to Do Before Treatment
- Spinal Cord Injury: Sensual Exercises
- Martha's Story: A Voice for Recovery
- Stan's Story: Getting There Hasn't Been Easy
- Debbie's Story: People Can and Do Recover
- Susan's Story: A Friend Really Helps
- Meniscus Tear: Rehabilitation Exercises
- Patellar Tracking Disorder: Exercises
- Stress Management: Breathing Exercises for Relaxation
- Good-Health Attitude
-
Sexual, Reproductive Health
- Menopause: Should I Use Hormone Therapy (HT)?
- Abnormal Uterine Bleeding: Should I Have a Hysterectomy?
- PMS: Should I Try an SSRI Medicine for My Symptoms?
- Sexual Orientation
- Gender Identity and Transgender Issues
- Heavy Menstrual Periods
- Pubic Lice
- Menopause and Your Risk for Other Health Concerns
- Menstrual Cups
- Gender Dysphoria
- Menstrual Cycle: Dealing With Cramps
- Men's Health
- Sexual and Reproductive Organs
- Sexual Health
- Women's Health
- Genital Warts
- Sexuality While Breastfeeding
- Premenstrual Syndrome (PMS)
- Chlamydia
- Sexuality and Physical Changes With Aging
- Relieving Menstrual Pain
- Uterine Fibroids
- Gonorrhea
- Syphilis
- Neurosyphilis
- Congenital Syphilis
- Emotions and Menopause
- Hot Flashes and Menopause
- Vaginal Dryness During and After Menopause
- Genital Herpes
- Parkinson's Disease and Sexual Problems
- Male Genital Problems and Injuries
- Menstrual Cramps
- Missed or Irregular Periods
- Genital Self-Examination
- Missed Periods and Endurance Training
- Rashes or Sores in the Groin
- Other Health Problems Caused by Herpes Simplex Virus
- Arrhythmias and Sexual Activity
- Stages of Syphilis
- Normal Vaginal Discharge
- Vaginal Rashes and Sores
- Vaginal Fistula
- Soy for Menopause Symptoms
- Menopause: Wild Yam and Progesterone Creams
- Normal Menstrual Cycle
- Vaginal Pessaries
- Uterine Fibroid Embolization (UFE)
- Uterine Fibroids: Should I Use GnRH-A Therapy?
- Uterine Fibroids: Should I Have Uterine Fibroid Embolization?
- Menopause: Managing Hot Flashes
- Premature Ejaculation
- High-Risk Sexual Behaviour
- Object in the Vagina
- Periodic Limb Movement Disorder
- Military Sexual Trauma
- Sexual Problems in Women
- Female Genital Problems and Injuries
- Smoking: Sexual and Reproductive Problems
-
Skin, Nails and Rashes
- Hidradenitis Suppurativa
- Removing Moles and Skin Tags
- Caregiving: Skin Care for Immobile Adults
- Yeast Skin Infection
- Bruises and Blood Spots Under the Skin
- Skin, Hair, and Nails
- Nail Psoriasis
- Phototherapy for Psoriasis
- Psoriasis
- Ringworm of the Skin
- Rash, Age 12 and Older
- Sunburn: Skin Types
- Heat Rash
- Colour Changes in Nails
- Changes in Your Nails
- Cut That Removes All Layers of Skin
- Skin Changes
- Venous Skin Ulcer
- Venous Skin Ulcers: Home Treatment
- Atopic Dermatitis: Taking Care of Your Skin
- Seborrheic Keratoses
- Care for a Skin Wound
- Psoriasis: Skin, Scalp, and Nail Care
- Protecting Your Skin From the Sun
- Skin Rashes: Home Treatment
- Skin Cyst: Home Treatment
- Calluses and Corns
- Calluses and Corns: Using Pumice Stones
- Calluses and Corns: Protective Padding
- Tazarotene (Psoriasis/Acne) - Topical
- Types of Acne
- Acne: Treatment With Benzoyl Peroxide
- Acne: Treatment With Alpha Hydroxy Acids
- Acne: Treatment With Salicylic Acid
- Acne: Treatment With Antibiotics
- Acne
- Acne: Tips for Keeping It Under Control
- Acne: Should I Take Isotretinoin for Severe Acne?
- Acne: Should I See My Doctor?
-
Thyroid
- Hyperthyroidism: Should I Use Antithyroid Medicine or Radioactive Iodine?
- Thyroid Storm
- Hyperparathyroidism
- Thyroid - Oral
- Subclinical Hypothyroidism
- Hypothyroidism
- Hyperthyroidism: Graves' Ophthalmopathy
- Radioactive Iodine for Hyperthyroidism
- Hyperthyroidism
- Thyroid Nodules
- Thyroid Hormone Production and Function
- Vertigo
- Check Your Symptoms
- Search Health Topics
Topic Overview
Is this topic for you?
This topic provides information about cancer of the lining of the uterus (endometrium). It does not cover cancer in the muscle of the uterus, which is called uterine sarcoma. This topic focuses on type I endometrial cancer, which is the most common kind of uterine cancer.
What is endometrial cancer?
Endometrial cancer is the growth of abnormal cells in the lining of the uterus. The lining is called the endometrium. Endometrial cancer is also called cancer of the uterus, or uterine cancer.
Endometrial cancer usually occurs in women older than 50. The good news is that it is usually cured when it is found early. And most of the time, the cancer is found in its earliest stage, before it has spread outside the uterus.
What causes endometrial cancer?
The most common cause of type I endometrial cancer is having too much of the hormone estrogen compared to the hormone progesterone in the body. This hormone imbalance causes the lining of the uterus to get thicker and thicker. If the lining builds up and stays that way, then cancer cells can start to grow.
Women who have this hormone imbalance over time may be more likely to get endometrial cancer after age 50.
What are the symptoms?
The most common symptoms include:
- Bleeding or vaginal discharge not related to your period (menstruation).
- Pain during sex.
- Pelvic pain.
How is endometrial cancer diagnosed?
Endometrial cancer is usually diagnosed with a biopsy. In this test, the doctor removes a small sample of the lining of the uterus to look for cancer cells.
How is it treated?
The main treatment for endometrial cancer is surgery to remove the uterus plus the cervix, ovaries, and fallopian tubes. This is called a hysterectomy with bilateral salpingo-oophorectomy. Other treatments include radiation therapy, hormone therapy, or chemotherapy.
Finding out that you have cancer can change your life. You may feel like your world has turned upside down and you have lost all control. Talking with family, friends, or a counsellor can really help. Ask your doctor about support groups. Or call the Canadian Cancer Society (1-888-939-3333) or visit its website at www.cancer.ca.
Health Tools
Health Tools help you make wise health decisions or take action to improve your health.
Cause
The main cause of most type I endometrial cancer is too much of the hormone estrogen compared to the hormone progesterone in the body. This hormone imbalance causes the lining of the uterus to get thicker and thicker. If the lining builds up and stays that way, then cancer cells can start to grow.
Symptoms
Unexpected vaginal bleeding after menopause is the most common symptom of endometrial cancer.
If you are taking hormone therapy after menopause, you can expect some bleeding. But if you have irregular bleeding, call your doctor.
Before menopause, abnormal bleeding or vaginal discharge is not as likely to be a sign of endometrial cancer. They are usually signs of other conditions, such as hormone changes.
Symptoms of more advanced endometrial cancer include:
- Pain in the pelvic area.
- A pelvic lump.
- Weight loss.
Symptoms of endometrial cancer can be mistaken for those of another condition, such as endometriosis.
What Happens
Normally, the lining of the uterus (endometrium) builds up and then sheds with each menstrual cycle. This shedding is menstrual bleeding, or a menstrual period.
But in most cases of endometrial cancer, the endometrium has built up and has not shed and thinned. The lining has remained thick. This is called endometrial hyperplasia. This is a "precancer" stage, and the cells can grow quickly and out of control. These fast-growing cells are cancer cells.
As the cancerous cells multiply, they form a mass of tissue, which can cause vaginal bleeding. Especially after menopause, this abnormal bleeding is a reason to call your doctor. Of women who have endometrial cancer after menopause, most have vaginal bleeding.
If endometrial cancer isn't treated, it may spread outside of the uterus. As it progresses, it may spread to the pelvic lymph nodes and other pelvic organs. Advanced-stage cancer may spread to lymph nodes and on to the lungs, liver, bones, brain, and vagina.footnote 1
The long-term outcome (prognosis) depends on the stage and grade of your cancer.
What Increases Your Risk
A risk factor for endometrial cancer is something that increases your chance of getting it. But it doesn't mean that you will definitely get it. And many people who get endometrial cancer don't have any risk factors.
The biggest risk factor for most endometrial cancers is related to the hormone estrogen. Estrogen is not a risk factor for endometrial cancer when it is balanced with another hormone, progesterone. But when estrogen is not kept in balance with progesterone, it can cause problems that raise a woman's risk for this cancer.
Risk factors for endometrial cancer include:
- Being obese. Fat cells make extra estrogen, but the body doesn't make extra progesterone to balance it out.
- Taking estrogen without taking a progestin.
- Taking tamoxifen. Tamoxifen reduces your risk for breast cancer but can increase your risk for endometrial cancer.
- Polycystic ovary syndrome. This can cause you to produce too much estrogen and not enough progesterone.
- Having naturally high levels of estrogen. This can cause women to start their periods before age 12 and delay menopause until after they are 52.
Other things that increase your risk include:
- Being older than 50. Endometrial cancer is most common in women older than 50.
- Inheriting some kinds of genes, such as those for Lynch syndrome.
- Having endometrial hyperplasia.
- Having type 2 diabetes.
- Never having been pregnant.
- Having previous radiation therapy to the pelvis.
When should you call your doctor?
See your doctor if you have:
- Abnormal vaginal bleeding or discharge, especially if it occurs after menopause.
- Pain during sex.
- Pain in the pelvic area.
- Irregular bleeding while taking hormone therapy.
If you have been diagnosed with cancer, be sure to follow your doctor's instructions about calling when you have problems, new symptoms, or symptoms that get worse.
Examinations and Tests
Tests to find cancer
To check your symptoms, your doctor will ask about your medical history and do a physical examination. This will include a pelvic examination.
An endometrial biopsy is needed to confirm a diagnosis of endometrial cancer. A biopsy removes a small sample of the lining of the uterus (endometrium) to be looked at under a microscope.
Other tests may include:
- A transvaginal pelvic ultrasound. This uses sound waves to create images of the uterus. The images can show how thick the endometrium is. A thick endometrium can be a sign of cancer in post-menopausal women. Ultrasound also can help show whether cancer has grown into the uterine muscle.
- A hysteroscopy. This allows your doctor to view the inside of the uterus and get an endometrial tissue sample.
- Dilation and curettage (D&C). This test is done to get a sample of tissue from the inside of the uterus. It may be done at the same time as a hysteroscopy.
Testing for endometrial cancer may show that you have endometrial hyperplasia. This is not cancer but may develop into cancer.
Tests to see if the cancer has spread
If cancer is found, surgery is done to find out how much the cancer has grown (stage and grade) and to treat it at the same time.
Before surgery, an imaging test may be done to see if cancer has spread to the abdomen and pelvis. This helps with planning for treatment. Imaging tests may include a CT scan or an MRI.
Other tests done before surgery may include:
- A complete blood count (CBC) to check for anemia and other abnormal blood values.
- A cancer antigen (CA) 125 test. This test helps to identify cancer that has or may spread (metastasize).
- A chest X-ray to check for cancer cells that have spread (metastasized) from the uterus.
Early detection
There is no routine screening test for endometrial cancer. The Canadian Cancer Society advises women who have an increased risk of endometrial cancer to talk with their doctors about a personal plan for testing.footnote 2
- Women are advised to report to their doctors any unexpected bleeding or spotting or unusual vaginal discharge.
- Women at risk for Lynch syndrome are advised to get checked every year starting at age 35. Having this risk also means a high risk of getting ovarian and/or uterine cancer.
High-risk women who have no pregnancy plans can avoid these cancers by having the uterus, fallopian tubes, and ovaries removed.footnote 3
Treatment Overview
Endometrial cancer found in its early stages can often be cured with surgery and close follow-up. Treatment choices depend on where the cancer is and how much it has grown.
Types of treatment
After testing shows that you have endometrial cancer, your doctor may recommend surgery to remove the uterus, ovaries, and fallopian tubes. All tissues removed in surgery are examined to find out the stage and grade of the cancer. Lymph nodes near the uterus may be examined to find out if cancer has spread outside of the uterus.
You may get more than one type of treatment for endometrial cancer. This depends on the size of the cancer and how the cancer cells look under the microscope. Treatments include:
- Surgery to remove the uterus (and cervix), ovaries, and fallopian tubes (hysterectomy with bilateral salpingo-oophorectomy).
- Surgery to remove lymph nodes.
- Radiation therapy to kill cancer cells.
- Progestin hormone therapy to block cancer growth.
- Chemotherapy to kill cancer cells.
You can find more information about endometrial cancer online at the:
- Canadian Cancer Society website at www.cancer.ca.
- U.S. National Cancer Institute website at www.cancer.gov
Clinical trials
Studies called clinical trials can be an option for women who don't want or aren't cured by standard treatments. Talk with your doctor to see if clinical trials are available and to find out if you are a good candidate.
Follow-up treatment
Endometrial cancer may come back (recur), so regular followup after your initial treatment is very important. Your doctor will set up a regular schedule of checkups that will happen less often as time goes on.
Most of the time when endometrial cancer comes back after treatment, a woman will have symptoms. These include:footnote 4
- Bleeding from the vagina, bladder, or rectum.
- Decreased appetite.
- Weight loss.
- Pain in your belly, hip, or back.
- Cough.
- Shortness of breath.
- Swelling in your belly or legs.
If you have any of these symptoms, see your doctor right away and don't wait for your next scheduled appointment.
Sexual problems and body changes
Your feelings about your body and your sexuality may change after treatment for cancer. It may help to talk openly with your partner about your feelings. Your doctor may be able to refer you to groups that can offer support and information.
Having cancer treatments such as radiation therapy or a hysterectomy may affect your ability to have or enjoy sex. If you do have sexual problems, talk with your doctor about treatment, information, or a group for support.
If you have not yet reached menopause, your menstrual period will end immediately after most treatments for endometrial cancer. If your uterus and ovaries have been removed or have had radiation therapy, your body will have a decrease in estrogen. This may cause:
- Menopausal symptoms, such as hot flashes, changes in mood, vaginal dryness, and atrophy (shrinking) of pelvic tissues. Talk with your doctor about how to manage your symptoms if they bother you. To learn more, see the topic Menopause and Perimenopause.
- An increased risk of heart disease and changes in your bones, such as osteoporosis.
Hospice palliative care
Cancer treatment has two main goals: curing cancer and making your quality of life as good as possible. Hospice palliative care can improve your quality of life by helping you to manage your symptoms. It can also help you with other concerns that you may have when you are living with a serious illness.
For some people who have advanced-stage cancer, a time comes when treatment to cure cancer no longer seems like a good choice. This can be because the side effects, time, and costs of treatment are greater than the promise of cure or relief. But this isn't the end of treatment. Hospice palliative care providers will work to help manage pain and other symptoms or side effects. They may help you decide what treatment you want or don't want. And they can help your loved ones understand how to support you.
It can be hard to decide when to stop treatment aimed at prolonging your life and shift the focus to end-of-life care. You and your doctor can decide when you may be ready for hospice palliative care.
Prevention
You cannot control some things that put you at risk for endometrial cancer, such as a family history of endometrial or colon cancer.
But you can make personal choices that lower your risk of endometrial cancer.
- Strive for a healthy body weight. The body's fat cells make estrogen. For more information on controlling your weight, see the topic Weight Management.
- Breastfeed if you are able. This decreases ovulation and estrogen activity.
- Get treatment for abnormal or unexpected bleeding. (Endometrial hyperplasia, which may develop into endometrial cancer, is one cause of abnormal bleeding.) Heavy menstrual periods, bleeding between periods, and bleeding after menopause are symptoms of hyperplasia.
- Exercise regularly. It may help control your weight and may reduce estrogen levels.
- Eat a diet that is low in animal fats and high in fruits and vegetables.
You have no risk for endometrial cancer if you have had your uterus removed (hysterectomy).
If you take tamoxifen
Tamoxifen is a breast cancer treatment that lowers your risk for having breast cancer come back (recur). But taking tamoxifen can raise your risk of getting endometrial cancer.
If you are taking tamoxifen, keep taking it as directed by your doctor. But be sure to have a pelvic examination each year. The risk of endometrial cancer from tamoxifen is less than the risk of getting breast cancer again.
If you are worried about endometrial cancer risk, talk with your doctor. You might be able to use another medicine, instead of tamoxifen, to reduce your risk for recurrent breast cancer.
Home Treatment
During treatment for endometrial cancer, you can do things at home to help manage your side effects and symptoms. If your doctor has given you instructions or medicines to treat these problems, be sure to also use them.
In general, healthy habits such as eating a balanced diet and getting enough sleep and exercise can help control your symptoms.
You can try home treatments:
- For nausea or vomiting, such as ginger or peppermint tea, gum, or candy.
- For diarrhea, such as taking small, frequent sips of water and bites of salty crackers.
- For constipation, such as plenty of water and fibre in your diet. Do not use a laxative without first talking to your doctor.
Other issues that can be treated at home include:
- Sleep problems. If you have trouble sleeping, try having a regular bedtime and getting exercise daily.
- Feeling very tired. If you lack energy or become weak easily, try to manage your energy and get extra rest.
- Hair loss. Hair loss may be unavoidable. But using mild shampoos and avoiding damaging hair products will reduce irritation of your scalp.
- Pain. Home treatment can help you manage pain. Be sure to talk with your doctor about any home treatment you use.
Handling the stress of having cancer
Having cancer can be very stressful. And it may feel overwhelming to face the challenges in front of you. Finding new ways of coping with the symptoms of stress may improve your overall quality of life.
These ideas may help:
- Get the support you need. Spend time with people who care about you. Let them help you.
- Take good care of yourself. Get plenty of rest, and eat nourishing foods.
- Talk about your feelings. Find a support group where you can share your experience.
- Try new ways to relax. And do things each day that help you stay calm and relaxed. Stress reduction techniques may help.
Medications
Medicines, such as chemotherapy or progestin hormone therapy, may be given after surgery for endometrial cancer. Your treatment depends on the stage and grade of the cancer and the risk for the cancer to spread or come back.
Medicine choices
Progestin hormone therapy may be used if your cancer has come back or spread or you are unable to have surgery or radiation therapy. Or it may be done if you are a young woman with early-stage cancer and you want the option of becoming pregnant in the future.
Chemotherapy is used alone or in combination. Examples include carboplatin, cisplatin, and doxorubicin.
Medicines to help with side effects
Nausea and vomiting are common side effects of chemotherapy. These side effects usually are temporary and go away when treatment is stopped. Your doctor will prescribe medicines to help relieve nausea.
Surgery
Surgery to remove the uterus (hysterectomy) is the most common treatment for endometrial cancer. Surgery has the highest cure rate of all treatments for endometrial cancer.
Along with the uterus (and cervix), the surgeon also removes the fallopian tubes, ovaries, and often the pelvic lymph nodes. Everything is then examined to find out the extent of the cancer and to help plan your treatment. If there are signs that more aggressive cancer still may be in the lymph system, more lymph nodes may be removed.
Surgery choices
- Hysterectomy with removal of the fallopian tubes and ovaries (bilateral salpingo-oophorectomy)
- Lymphadenectomy(removal of lymph nodes)
What to think about
Most women have their ovaries removed after a diagnosis of endometrial cancer. This is to make sure the cancer has not spread to the ovaries, to reduce the production of estrogen, and to slow cancer growth.
If you're still in your child-bearing years, a hysterectomy means that pregnancy will no longer be possible and that your menstrual periods will end. The hormonal changes of menopause will begin as soon as your ovaries are removed. For more information, see the topic Menopause and Perimenopause.
Other Treatment
Radiation therapy
Radiation therapy may be used to treat endometrial cancer. Radiation may be given internally by placing radioactive substances in the vagina (vaginal radiation). Or it may be given externally by delivering radiation from an outside source (pelvic radiation).
Radiation therapy may also be used for endometrial cancer that has come back. If the cancer has come back only in the vagina, radiation can sometimes cure the cancer. Radiation also may be used to control symptoms and increase comfort.
If you need to have radiation, your doctor will plan the most effective treatment for you based on the stage and grade of your cancer.
Complementary therapies
People sometimes use complementary therapies along with medical treatment to help relieve symptoms and side effects of cancer treatments. Some of these therapies that may be helpful include:
- Acupuncture to relieve pain.
- Breathing exercises for relaxation.
- Massage and biofeedback to reduce pain and ease tension.
- Meditation or yoga to relieve stress.
Mind-body treatments like the ones listed above may help you feel better. They can make it easier to cope with cancer treatments. They also may reduce chronic low back pain, joint pain, headaches, and pain from treatments.
Before you try a complementary therapy, talk to your doctor about the possible value and potential side effects. Let your doctor know if you are already using any such therapies. They are not meant to take the place of standard medical treatment.
Related Information
References
Citations
- National Cancer Institute (2012). Endometrial Cancer Treatment (PDQ)—Health Professional Version. Available online: http://www.cancer.gov/cancertopics/pdq/treatment/endometrial/HealthProfessional.
- Canadian Cancer Society (2012). Uterine cancer overview. Canadian Cancer Encyclopedia. Available online: http://info.cancer.ca/cce-ecc/default.aspx?Lang=E&toc=53#Early_detection.
- Schmeler KM, et al. (2006). Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome. New England Journal of Medicine, 354(3): 261–269.
- National Comprehensive Cancer Network (2012). Uterine neoplasms. NCCN Clinical Practice Guidelines in Oncology, version 3. Available online: http://www.nccn.org/professionals/physician_gls/f_guidelines.asp#site.
Other Works Consulted
- American Cancer Society (2012). Cancer Facts and Figures 2012. Atlanta: American Cancer Society. Available online: http://www.cancer.org/Research/CancerFactsFigures/CancerFactsFigures/cancer-facts-figures-2012.
- American College of Obstetricians and Gynecologists (2005, reaffirmed 2011). Management of endometrial cancer. ACOG Practice Bulletin No. 65. Obstetrics and Gynecology, 106(2): 413–425.
- Dowdy SC, et al. (2012). Uterine cancer. In JS Berek, ed., Berek and Novak's Gynecology, 15th ed., pp. 1250–1303. Philadelphia: Lippincott Williams and Wilkins.
- McMeekin DS, et al. (2009). Corpus: Epithelial tumors. In RR Barakat et al., eds., Principles and Practice of Gynecologic Oncology, 5th ed., chap. 23, pp. 683–732. Philadelphia: Lippincott Williams and Wilkins.
- National Cancer Institute (2012). Endometrial Cancer Treatment (PDQ)—Health Professional Version. Available online: http://www.cancer.gov/cancertopics/pdq/treatment/endometrial/HealthProfessional
- National Cancer Institute (2012). Endometrial Cancer Treatment (PDQ)—Patient Version. Available online: http://www.cancer.gov/cancertopics/pdq/treatment/endometrial/Patient.
- National Comprehensive Cancer Network (2012). Uterine neoplasms. NCCN Clinical Practice Guidelines in Oncology, version 3. Available online: http://www.nccn.org/professionals/physician_gls/f_guidelines.asp#site.
Credits
Current as of: September 8, 2021
Author: Healthwise Staff
Medical Review:
Sarah Marshall MD - Family Medicine
Femi Olatunbosun MB, FRCSC - Obstetrics and Gynecology
E. Gregory Thompson MD - Internal Medicine
Adam Husney MD - Family Medicine
Kathleen Romito MD - Family Medicine
Ross Berkowitz MD - Obstetrics and Gynecology
Current as of: September 8, 2021
Author: Healthwise Staff
Medical Review:Sarah Marshall MD - Family Medicine & Femi Olatunbosun MB, FRCSC - Obstetrics and Gynecology & E. Gregory Thompson MD - Internal Medicine & Adam Husney MD - Family Medicine & Kathleen Romito MD - Family Medicine & Ross Berkowitz MD - Obstetrics and Gynecology
This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use and Privacy Policy. Learn how we develop our content.
Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.