Rabies is a very serious and usually fatal disease caused by one of a number of rabies viruses. If you are bitten or scratched by an animal that may have rabies, or seems sick and behaves strangely, it is crucial to begin preventative treatment for rabies as soon as possible. This includes washing the wound well and seeking medical care.
The rabies vaccine is a three-shot series. Make sure to schedule the first shot at least 21 to 28 days before your trip.
If you want the rabies vaccine and will also be taking mefloquine or chloroquine to prevent malaria, consult with your immunization provider to discuss the potential for any additional doses of rabies vaccine. (But you can get the post-exposure rabies vaccine at the same time as the malaria drugs without any problem.)