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… born with severe birth defects. Other serious side effects are rare. Health Canada and the U.S. Food and Drug Administration (FDA) warn that … the online document some Information (e.g. cross-references to other topics, definitions or medical illustrations) is only available in the … and the Healthwise logo are trademarks of Healthwise, Incorporated. … aa37467 … Acne Should I Take Isotretinoin for Severe Acne …