Aspirin Suppository - Rectal

Pronunciation: AS-pir-in

Common Brand Name(s): Supasa

Important: How To Use This Information

This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

Uses

This medication is used to reduce fever and relieve minor to moderate pain from conditions such as muscle aches, toothaches, menstrual cramps, arthritis, and headaches. Aspirin is known as a salicylate and a nonsteroidal anti-inflammatory drug (NSAID) that works by blocking a certain natural substance in your body to reduce pain and swelling.

Aspirin is also used in low doses as a blood thinner to prevent blood clots after surgery on clogged arteries (e.g., bypass surgery, carotid endarterectomy) and to reduce the risk of stroke or heart attack.

How To Use

If you are using this medication for self-treatment, carefully read the product label to make sure this product is correct for you or your child. You should also read the product label to find recommendations on the maximum number of suppositories you can use in a 24-hour period, and the maximum length of self-treatment before seeking medical advice. Talk to your doctor or pharmacist if you have any questions about this medication. If you are using this medication under the instruction of your doctor, use it exactly as prescribed.

Apply this medication rectally as directed by your doctor, or, if you are self-treating, follow instructions on the product label. If the suppository is too soft to insert, put it in cold water or refrigerate for 30 minutes before removing the foil wrapper. Unwrap the foil and moisten the suppository with a little water. Lie down on your left side with right knee bent. Insert the suppository into the rectum with your finger. Remain lying down for a few minutes and avoid having a bowel movement for an hour or longer so the drug will be absorbed.

The dosage and length of aspirin treatment are based on your medical condition and response to therapy. Consult your doctor before treating a child younger than 12. This medication should not be used for self-treatment of pain for longer than 10 days in adults or 5 days in children. This drug should not be used in adults or children for fever persisting longer than 3 days or for sore throat pain lasting longer than 2 days. No more than 5 doses of this medication should be given to a child for pain or fever in a 24-hour period. Do not use more medication or use it for longer than recommended above unless directed by your doctor. Use the smallest effective dose. Consult your doctor or pharmacist if you have any questions.

If you are using this medication for self-treatment of headache, seek immediate medical attention if you also have slurred speech, weakness on one side of the body, or sudden vision changes. Before using this drug, consult a doctor or pharmacist if you have headaches caused by head injury, coughing, or bending, or if you have a headache with persistent/severe vomiting, fever, and stiff neck.

If you are using this medication on an as needed basis (not on a regular schedule), remember that pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has significantly worsened, the medicine may not work as well.

Consult your doctor if your condition persists or worsens (for example, if you have new or unusual symptoms, redness/swelling of the painful area, pain/fever that does not go away or gets worse).

Side Effects

Irritation of the rectal area may occur. If this effect persists or worsens, notify your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including:

  • easy bruising/bleeding
  • difficulty hearing
  • ringing in the ears
  • signs of kidney problems (such as change in the amount of urine)
  • persistent or severe nausea/vomiting
  • unexplained tiredness
  • dizziness
  • dark urine
  • yellowing of the eyes/skin

This drug may rarely cause serious bleeding from the stomach/intestine or other areas of the body. If you notice any of the following very serious side effects, get medical help right away:

  • black/tarry stools
  • persistent or severe stomach/abdominal pain
  • vomit that looks like coffee grounds
  • slurred speech
  • weakness on one side of the body
  • sudden vision changes or severe headache

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking aspirin, tell your doctor or pharmacist if you are allergic to it; or to other salicylates (e.g., choline salicylate); or to other pain relievers or fever reducers (acetaminophen, NSAIDs such as ibuprofen, naproxen); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

If you have any of the following health problems, consult your doctor or pharmacist before using this medication:

  • kidney or liver disease
  • diabetes
  • stomach problems (e.g., ulcers, heartburn, stomach pain)
  • bleeding/blood-clotting disorders (e.g., hemophilia, vitamin K deficiency, low platelet count)
  • aspirin-sensitive asthma (a history of worsening breathing with runny/stuffy nose after taking aspirin or other NSAIDs)
  • growths in the nose (nasal polyps)
  • gout
  • anemia
  • certain enzyme deficiencies (pyruvate kinase or G6-PD deficiency)

This medicine may cause stomach bleeding. Daily use of alcohol and tobacco, especially when combined with this product, may increase your risk for this side effect. Limit alcoholic beverages, and stop smoking. Check with your doctor or pharmacist for more information.

Before having surgery, tell your doctor or dentist that you are using this medication.

Older adults may be more sensitive to the side effects of this drug, especially stomach/intestinal bleeding and ulcers.

This drug contains aspirin. Children and teenagers less than 18 years old should not use aspirin if they have chickenpox, influenza or any undiagnosed illness without first consulting a doctor about Reyes syndrome, a rare but serious illness.

Aspirin is not recommended for use to treat pain or fever during pregnancy. It may harm an unborn baby or cause problems during delivery. Consult your doctor before using this medication if you are or think you may be pregnant. In some cases, low-dose aspirin (40-150 milligrams a day) may be used safely during pregnancy to prevent certain conditions. Talk to your doctor for more details.

Aspirin passes into breast milk. When used in large amounts (such as to treat pain or fever), it may harm a nursing infant and breast-feeding while using this drug is not recommended. However, low-dose aspirin for heart attack or stroke prevention may be used if directed by your doctor. Consult your doctor before breast-feeding.

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include:

  • acetazolamide
  • "blood thinners" (such as warfarin, heparin)
  • corticosteroids (such as prednisone)
  • dichlorphenamide
  • ketorolac
  • methotrexate
  • mifepristone
  • certain medications for gout (such as probenecid, sulfinpyrazone)
  • anti-seizure drugs (such as phenytoin, valproic acid)
  • herbal medications (such as ginkgo biloba)

Before using this product, consult your doctor if your child has recently received certain live vaccines (such as varicella vaccine, live influenza vaccine).

Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers known as NSAIDs (non-steroidal anti-inflammatory drugs such as ibuprofen, naproxen). To prevent an overdose of aspirin, read the labels carefully before taking other pain relievers or cold products to make sure they do not contain aspirin. Ask your pharmacist about the safe use of these products.

This medication may interfere with certain laboratory tests (including certain urine sugar tests), possibly causing false test results. Make sure laboratory personnel and your doctors know you are taking this medication.

Overdose

This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: burning pain in the throat/stomach, confusion, mental/mood changes, fainting, weakness, ringing in the ears, fever, rapid breathing, change in the amount of urine, seizures, loss of consciousness.

Notes

Do not share this medication with others.

If you use this medication regularly or at high doses, laboratory and/or medical tests (e.g., liver and kidney function tests, blood count, salicylate level) may be performed to monitor your progress or check for side effects. Consult your doctor for more details.

There are many different dosage forms for aspirin products. Ask your doctor or pharmacist for recommendations on the best product for you.

Missed Dose

If you are prescribed this drug on a regular schedule (not just "as needed") and you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

Storage

Store refrigerated or at a cool place between 35-59 degrees F (between 2-15 degrees C). Keep away from moisture and light. Do not store in the bathroom. Do not use any aspirin product that has a strong vinegar-like smell.

Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Is it an emergency?

If you or someone in your care has chest pains, difficulty breathing, or severe bleeding, it could be a life-threatening emergency. Call 9-1-1 or the local emergency number immediately.
If you are concerned about a possible poisoning or exposure to a toxic substance, call Poison Control now at 1-800-567-8911.

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