Common Brand Name(s): Combantrin
Important: How To Use This Information
This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
This medication is used to treat intestinal worm infections such as pinworm, roundworm, and hookworm. Pyrantel belongs to a class of drugs known as anthelmintics. It works by making the worms unable to move (paralyzed) so that the body can remove them naturally in the stool.
This medication may be used to self-treat pinworm infections. For other types of worm infections (such as roundworm, hookworm), use this product only as directed by your doctor. Do not use this medication in children younger than 2 years unless directed by the doctor.
How To Use
If you are taking the over-the-counter product, read all directions on the product package before taking this medication. This medicine comes with a Patient Information Leaflet. Read it carefully. Be sure you understand how to identify pinworms, understand the symptoms of pinworm infections, and how to prevent becoming infected again. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth with or without food, usually once as a single dose or as directed by your doctor. If you are using the chewable tablets, chew each tablet well and swallow. This medication may be taken with milk or fruit juice. It is not necessary to take a laxative with this medication.
Dosage is based on your weight, type of infection, and response to treatment. Do not take more than a total of 1 gram in a single dose. If you are self-treating for pinworms, take the medication once only. Do not repeat the dose without talking with your doctor first. Depending on the type of worm infection you have, your doctor may direct you to take the medication only once or for several days. Your doctor may also direct you to repeat the dose in 2 weeks.
If you continue to see worms in your stool or if symptoms persist or worsen, or if you think you may have a different type of worm infection or a serious medical problem, seek immediate medical attention.
Nausea, vomiting, diarrhea, stomach/abdominal cramps, headache, drowsiness, dizziness, trouble sleeping, or loss of appetite may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including:
- itching/swelling (especially of the face/tongue/throat)
- severe dizziness
- trouble breathing
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Before taking pyrantel, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of:
- liver disease
- severe lack of nutrition (malnutrition)
This drug may rarely make you drowsy or dizzy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
Chewable tablets may contain aspartame. If you are taking the chewable tablets and have phenylketonuria (PKU) or any other condition that requires you to restrict your intake of aspartame (or phenylalanine), consult your doctor or pharmacist about using the chewable tablets safely.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. If you are pregnant, do not use this medication to treat yourself without first consulting your doctor.
It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.
The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.
If you are taking this medication under your doctor's direction, to help your doctor or pharmacist give you the best care, be sure to tell your doctor or pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.
Keep a list of all the products you use. Share the list with your doctor and pharmacist to reduce your risk for serious medication problems.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe muscle spasms/twitching/weakness or severe trouble breathing.
Some types of worm infections can be easily spread among family members or people living within the same household. It is important for family members to be checked even if they do not have symptoms. To keep from being infected again, everyone in the household may need to be treated. Also, thoroughly clean the home and all clothing, and be very careful with personal hygiene. Wash hands frequently and keep fingernails trimmed. Consult your doctor or pharmacist for details.
If your doctor has directed you to use this medication, use it for your current condition only. Do not use it later for another infection unless your doctor tells you to.
If your doctor has directed you to use more than one dose and you miss a dose, contact your doctor or pharmacist right away to establish a new dosing schedule.
Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Information last revised October 2018.
Copyright(c) 2018 First Databank, Inc.
Conditions of use: The information in this database is intended to supplement, not substitute for the expertise and judgment of healthcare professionals. The information in not intend to cover all possible uses, directions, precautions, drug interactions or adverse effects nor should it be construed in indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.