Trimeprazine - Oral

Pronunciation: trye-MEP-ra-zeen

Common Brand Name(s): Panectyl

Important: How To Use This Information

This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

Uses

Trimeprazine is an antihistamine used to reduce itching from allergies, hives, eczema, and other causes (e.g., insect bites, chickenpox, reactions to certain drugs). It may also be used to treat cough from various causes (e.g., throat irritation, asthma, allergy, hay fever). This medication works by blocking certain natural substances (histamine, acetylcholine) that your body makes. To reduce itching and cough, it may also act directly on certain parts of the brain.

This medication should not be used to treat cough due to a cold - or to make a child sleepy - if the child is less than 2 years old.

How To Use

Take this medication by mouth with or without food as directed by your doctor. This medication may be taken with food or milk if stomach upset occurs.

The dosage is based on your age, medical condition, and response to therapy. Do not increase your dose or take this medication more often without your doctor's approval. Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Inform your doctor if your condition persists or worsens.

Side Effects

Drowsiness, dizziness, headache, stomach upset, blurred vision, decreased coordination, or dry mouth/nose/throat may occur. These effects may decrease as your body adjusts to the medication. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur:

  • agitation/restlessness
  • face/muscle twitching
  • mental/mood changes (e.g., hallucinations, depression, nervousness)
  • shaking (tremors)
  • trouble urinating
  • uncontrolled movements

Tell your doctor right away if any of these rare but very serious side effects occur:

  • easy bruising/bleeding
  • fast/irregular heartbeat
  • seizure

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to phenothiazines (e.g., chlorpromazine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • blood disorders (e.g., bone marrow depression)
  • breathing problems (e.g., asthma, emphysema)
  • a certain eye problem (glaucoma)
  • heart problems
  • high blood pressure
  • liver disease
  • seizures
  • stomach/intestinal problems (e.g., ulcers, blockage)
  • overactive thyroid (hyperthyroidism)
  • urination problems (e.g., trouble urinating due to enlarged prostate, urinary retention)

This drug may make you dizzy or drowsy or blur your vision. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

To minimize dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

The elderly may be more sensitive to the effects of this drug, especially dizziness, drowsiness, and low blood pressure.

Do not give this medication to a child under 6 years unless directed to do so by a doctor. Children who are very ill or have a dangerous loss of body fluids (dehydration) may be more sensitive to certain side effects of this drug (e.g., seizures). In young children, this medication may cause agitation/excitement instead of drowsiness.

During pregnancy, this drug should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This medication passes into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or other antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: large pupils, flushing, fever, hallucinations, weakness, shaking (tremors), muscle twitching, loss of consciousness, seizures. In children, excitement may occur first, and may be followed by loss of coordination, drowsiness, loss of consciousness, seizures.

Notes

Do not share this medication with others.

Do not take this drug for several days before allergy testing because test results can be affected.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of your next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Is it an emergency?

If you or someone in your care has chest pains, difficulty breathing, or severe bleeding, it could be a life-threatening emergency. Call 9-1-1 or the local emergency number immediately.
If you are concerned about a possible poisoning or exposure to a toxic substance, call Poison Control now at 1-800-567-8911.

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