Drug resistance (such as antibiotic resistance) occurs when
disease-causing organisms change over time and adapt in ways that allow them to
survive exposure to a medicine that in the past killed or controlled them.
Many kinds of bacteria have become resistant to common antibiotics
designed to kill them. These are called antibiotic-resistant bacteria. For
example, several strains of the bacteria that cause tuberculosis and sinus,
ear, and lung infections can no longer be killed by many antibiotics. Other
illnesses, such as malaria and gonorrhea, also have drug-resistant strains of
Frequent and/or inappropriate use of antibiotics leads to the
development of drug-resistant bacteria. For example, taking antibiotics when
they may not be needed, using them for a non-bacterial infection (such as a
cold), or not taking all of an antibiotic as directed may promote the
development of antibiotic-resistant strains of bacteria.
E. Gregory Thompson, MD - Internal Medicine & Brian D. O'Brien, MD - Internal Medicine & Theresa O'Young, PharmD - Clinical Pharmacy