Immunizations That May Cause Fever

Short-term, mild reactions to immunizations are common. Immunizations that may cause a fever include:

  • Diphtheria, tetanus, acellular pertussis (DTaP) or diphtheria, pertussis, tetanus (DPT). Babies can have a fever of up to 39.5°C (103.1°F) axillary. within 2 to 3 hours of getting the DTaP or DPT shot. Children may be fussy and have other mild symptoms such as poor appetite, sleepiness, or redness and swelling at the shot site for a few days.
  • Measles, mumps, and rubella (MMR). The shot site may become red, swollen, hard, and slightly warm within the first 24 to 48 hours. Fever also may occur up to 2 weeks after the shot. A mild rash may develop up to 3 weeks after the shot.

Current as of: June 26, 2019

Author: Healthwise Staff
Medical Review:
William H. Blahd Jr. MD, FACEP - Emergency Medicine
Adam Husney MD - Family Medicine
Kathleen Romito MD - Family Medicine
David Messenger MD

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