Topic Overview

Between 1948 and 1971, millions of women took a drug called diethylstilbestrol (DES) to prevent miscarriage.

Daughters born to women who took DES while pregnant have a slightly higher risk of developing:

  • Abnormal cervical cells that cause an abnormal Pap test result.
  • Cancer of the vagina.
  • Structural problems in the reproductive organs (such as a T-shaped uterus), which can cause infertility.

Related Information


ByHealthwise Staff
Primary Medical Reviewer Sarah Marshall, MD - Family Medicine
Femi Olatunbosun, MB, FRCSC - Obstetrics and Gynecology
Specialist Medical Reviewer Kirtly Jones, MD - Obstetrics and Gynecology

Current as ofFebruary 20, 2015