Scleroderma is a rare disease in which a person's immune system begins to destroy normal, healthy tissues. (This is called an autoimmune disease.) As a result, connective tissue of the skin, lungs, and internal organs—especially the esophagus, kidneys, and digestive tract—is replaced with scar tissue. This change causes the tissues to become stiff and the muscles to not work as well.
Author: Healthwise Staff Medical Review: Adam Husney MD - Family Medicine Brian D. O'Brien MD - Internal Medicine Martin J. Gabica MD - Family Medicine Kathleen Romito MD - Family Medicine Peter J. Kahrilas MD - Gastroenterology
Medical Review:Adam Husney MD - Family Medicine & Brian D. O'Brien MD - Internal Medicine & Martin J. Gabica MD - Family Medicine & Kathleen Romito MD - Family Medicine & Peter J. Kahrilas MD - Gastroenterology