Huntington's disease is a rare condition that causes parts of the brain to break down, or degenerate. It is also called Huntington's chorea. The disease causes rapid, jerky body movements and the loss of normal mental abilities (dementia). Huntington's disease can cause personality changes, behaviour problems, and memory loss. Symptoms usually develop after age 40. There is no known cure. But treatment with medicines may help control the involuntary movements and behaviour changes.
Huntington's disease is caused by a changed, or mutated, gene. If you have a parent with the disease, you have a 50% chance of getting the changed gene and the disease. But there is no way to know when you will develop Huntington's disease. Some people may pass on the changed gene to a child before knowing that they have the changed gene.
A blood test can show whether you have the changed gene. You may want to have genetic counselling if you are thinking of having the test. Genetic counsellors are experts who can explain what the test means, tell you the benefits and risks of the test, and answer your questions. But you make the decision about whether to have the test.
If you have a family member who has Huntington's disease, their blood usually is tested first to identify the changed gene that might run in your family. Then you give a blood sample, which is screened for the gene change. Testing another family member also may be important in case your family's DNA is unusual in some way that might affect the test result.
Although this test is highly reliable, no test is 100% accurate. Also, if you test positive, the test can't tell you when you will develop Huntington's disease or how quickly the disease will advance.
The decision to take the test for Huntington's disease is personal. You may have emotional, financial, and family reasons for taking or not taking the test.
You might choose to be tested because:
You might choose not to be tested because:
|Canadian Association of Genetic Counsellors (CAGC)|
|PO Box 52083|
|Oakville, ON L6J 7N5|
The Canadian Association of Genetic Counsellors (CAGC) is a professional organization of genetic counsellors, physicians, social workers, and students in related fields.
|Huntington's Disease Society of America|
|505 Eighth Avenue|
|New York, NY 10018|
The Huntington's Disease Society of America is dedicated to improving the lives of people who have Huntington's disease and their families. It promotes and supports research and medical efforts to eradicate Huntington's disease and assists families affected by it to cope with the problems it can cause. The Society also provides materials to educate the public and health professionals about Huntington's disease.
Other Works Consulted
- Fischbach FT, Dunning MB III, eds. (2009). Manual of Laboratory and Diagnostic Tests, 8th ed. Philadelphia: Lippincott Williams and Wilkins.
- Olanow CW (2008). Hyperkinetic movement disorders. In AS Fauci et al., eds., Harrison's Principles of Internal Medicine, 17th ed., vol. 2, pp. 2560–2565. New York: McGraw-Hill.
|Primary Medical Reviewer||Sarah Marshall, MD - Family Medicine|
|Specialist Medical Reviewer||Siobhan M. Dolan, MD, MPH - Reproductive Genetics|
|Last Revised||December 29, 2011|
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