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This topic covers depression in adults. For information on:
Depression is an illness that causes you to feel sad, to lose interest in activities that you've always enjoyed, to withdraw from others, and to have little energy. It's different from normal feelings of sadness, grief, or low energy. Depression can also cause people to feel hopeless about the future and even to think about suicide.
Many people, and sometimes their families, feel embarrassed or ashamed about having depression. Don't let these feelings stand in the way of getting treatment. Remember that depression is a common illness. Depression affects the young and old, men and women, all ethnic groups, and all professions.
If you think you may be depressed, tell your doctor. Treatment can help you enjoy life again. The sooner you get treatment, the sooner you will feel better.
Depression is a disease. It's not caused by personal weakness and is not a character flaw. When you have depression, chemicals in your brain called neurotransmitters are out of balance.
Most experts believe a combination of family history (your genes) and stressful life events may cause depression. Life events can include:
Just because you have a family member with depression or have stressful life events doesn't mean you'll get depression.
You also may get depressed even if there is no reason you can think of.
The symptoms of depression may be hard to notice at first. They vary among people, and you may confuse them with just feeling "off" or with another health problem.
The two most common symptoms of depression are:
A serious symptom of depression is thinking about death or suicide. If you or someone you care about talks about this or feeling hopeless, get help right away.
You also may:
If you have some of these symptoms for at least 2 weeks, talk to your doctor. Treatment may be right for you.
If you think you may have depression, take a short quiz to check your symptoms:
Depression can be treated in various ways. Counselling, psychotherapy, and/or antidepressant medicines are all used. Lifestyle changes, such as getting more exercise, also may help. Your doctor or mental health professional will help you find the best treatment.
If you have mild or moderate depression, your family doctor or a mental health professional, such as a counsellor or psychologist, may treat you. If you have severe depression or if treatment is not helping, you may need to see a psychiatrist. Some people need to be treated in the hospital, especially if they have thoughts of suicide.
Work with your health care team to find the best treatment for you. It may take a few tries, and it can take several weeks for the medicine to start working. Try to be patient and keep following your treatment plan.
Depression can return (relapse). How likely you are to get depression again increases each time you have a bout of depression. Taking your medicines and continuing some types of therapy after you feel better can help keep that from happening. Some people need to take medicine for the rest of their lives. This does not stop them from living full and happy lives.
Let your doctor know if you think you are depressed. Depression is easy to overlook. The earlier you are treated, the more quickly you will get better.
If someone you care for is depressed, the best thing you can do is help the person get or stay in treatment. Learn about the disease. Talk to the person and gently encourage him or her to do things and see people. Don't get upset with the person. The behaviour you see is the disease, not the person.
Many people who have depression have thoughts of death or thoughts of suicide, and depression can lead to suicide. Learn the warning signs of suicide, which include talking a lot about death, giving things away, or using a lot of alcohol or drugs or both. If you see these signs in yourself or a loved one, get help.
Call 911 or check your local phone book or provincial website for resources on getting help in your area if you (or someone you care about who has depression):
If a suicide threat seems real, call 911, a suicide hotline, or the police. Stay with the person, or ask someone you trust to stay with the person, until the crisis has passed. Don't argue or challenge the person. Tell the person you don't want him or her to die.
Frequently Asked Questions

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| Interactive Tool: Are You Depressed? | |
Depression is a disease. It is not caused by personal weakness and is not a character flaw. When you have depression, chemicals in your brain called neurotransmitters are out of balance.
Most experts believe a combination of family history (your genes) and stressful life events may cause depression.
Sometimes even happy life events, such as a marriage or promotion, can trigger depression because of the stress that comes with change.
Just because you have a family member with depression or have stressful life events doesn't mean you'll get depression. You also may get depression without going through a stressful event.
Health problems also can cause depression. For example, both anemia and an underactive thyroid gland (hypothyroidism) can lead to depression. Treating the health problem usually cures the depression.
Certain medicines, such as steroids or narcotics, can cause depression. If you stop using the medicine, the depression may go away.
The symptoms of depression may be hard to notice at first. They can be different from person to person, and you may confuse them with just feeling "off" or "down." You also may confuse the symptoms with another health problem.
The two most common symptoms of depression are:
A serious symptom of depression is thinking about death and suicide. If you or someone you care about talks about suicide or feeling hopeless, get help right away.
You also may:
If you have at least five of the above symptoms for 2 weeks or longer, and one of the symptoms is either sadness or loss of interest, you may have depression and may need treatment. If you have 2 to 4 symptoms for a period of at least 2 years (1 year for a child), you may have a long-term form of depression called dysthymic disorder (dysthymia).
Even if you have fewer symptoms, you may still be depressed and may benefit from treatment. No matter how many symptoms you have, it's important to see your doctor. The sooner you get treatment, the better your chance for a quick and full recovery.
It's possible to have periods of both energy and elation (mania) and depression. This may be bipolar disorder. If this happens to you, tell your doctor. The treatments for depression and bipolar disorder are different. For more information, see the topic Bipolar Disorder.
If you think you may have depression, take a short quiz to check your symptoms:
![]() One Woman's Story: "I woke up every day with suicide on my mind, and I went to bed with suicide on my mind."—Martha |
Symptoms can be mild, moderate, or severe:
Depression can affect your physical health. You may have headaches or other aches and pains or have digestive problems such as constipation or diarrhea. You may have trouble having sex or may lose interest in it. If you notice any of these changes, talk to your doctor. Your doctor may be able to help.
Many women have mood changes before menstruation. This may be a sign of premenstrual syndrome (PMS). But if your premenstrual mood changes and other PMS symptoms are making daily life hard or harming your relationships, you may have a type of depression known as premenstrual dysphoric disorder (PMDD). To learn more about this, see the topic Premenstrual Syndrome (PMS).
Women also may feel sad after having a baby. But if you feel very sad after you've had your baby, see your doctor. You may have postpartum depression. For more information, see the topic Postpartum Depression.
Symptoms of depression may be different for older adults. Depression can make older adults confused or forgetful or cause them to stop seeing friends and doing things. It can be confused with problems like dementia.
Symptoms of depression in children and teens can be different from adult symptoms. These symptoms include doing poorly in school, having temper tantrums, and becoming sexually active. For more information, see the topic Depression in Children and Teens.
Thoughts of suicide are common in people who have depression. Most people do not act on these thoughts, but they must be taken seriously.
Call 911 or check your local phone book or provincial website for resources on getting help in your area if you (or someone you care about who has depression):
Learn about depression and suicide and the warning signs of suicide, such as giving away things or suddenly using lots of alcohol or drugs or both.
Warning signs of suicide in children and teens may include running away from home or doing risky or dangerous things, such as driving drunk or abusing drugs. If you see warning signs in yourself or a loved one, get help.
Depression is different for everyone.
For some people, a bout of depression begins with symptoms of anxiety (such as worrying a lot), sadness, or lack of energy. This may go on for days or months before you or others think you are depressed. And other people may feel depressed suddenly. This may happen after a big change in life, such as the loss of a loved one or a serious accident.
It's possible to have periods of both energy and elation (mania) and depression. This may be bipolar disorder. If this happens to you, tell your doctor. The treatments for depression and bipolar disorder are different. For more information, see the topic Bipolar Disorder.
If you don't get treated, depression may last from months to a year or longer. A small number of people feel depressed for most of their lives and always need treatment.
Depression can return, which is called a relapse. At least half of the people who have depression once get it again.1 How likely you are to get depression again increases each time you have a bout of depression. You can make having another bout of depression less likely by following your treatment plan and using your medicines.
Depression is linked with many health concerns. These include other diseases, drug or alcohol use, and pregnancy.
If you have depression and another health concern, you need to deal with both of them. Read about:
Experts don't know why some people get depression and others don't. But certain things make you likely to get depression. These are called risk factors.
Important risk factors for depression include:
Other risk factors include:
Medical problems also may cause depression or make it worse. These problems include:
Women may have other risk factors. These include:
Call 911, your provincial health information line, or other emergency services right away if:
Call a doctor right away if:
Seek care soon if:
If you have not been diagnosed with depression, but you think you may be depressed, use the Feeling Depressed topic to check your symptoms.
There any many types of professionals who treat depression and many types of treatments. A good place to start is with your family doctor or general practitioner. If treatment by your doctor does not help you, you may be referred to a specialist such as a psychiatrist.
Whomever you see, it is important that this person has experience treating people with depression and is trained in proven therapies. It is also important that you establish a good long-term relationship. If you don't feel comfortable with one doctor or therapist, try another one.
Treatment such as professional counselling or therapy can be provided by:
Other health professionals who also may be trained in treating depression include:
Depression may be diagnosed when you talk to your doctor about feeling sad or when your doctor asks you questions and discovers that you are feeling sad. You may be seeing your doctor because you feel sad or because you have another health problem or concern.
If your doctor thinks you are depressed, he or she will ask you questions about your health and feelings. This is called a mental health assessment. Your doctor also may:
Depending on your history and risk factors, your doctor may order other tests.
If you are depressed, your doctor may treat you or refer you for therapy to treat your symptoms.
Always tell your doctor if you feel sad or have other symptoms of depression. Many times, people are embarrassed by these feelings and say nothing. Depression can be treated, and the sooner you get treatment, the better your chance for a quick and full recovery.
It's possible to have periods of both energy and elation (mania) and depression. This may be bipolar disorder. If this happens to you, tell your doctor. The treatments for depression and bipolar disorder are different. For more information, see the topic Bipolar Disorder.
If you have depression only during certain seasons of the year, such as the fall and winter months, tell your doctor. You may have seasonal affective disorder. For more information, see the topic Seasonal Affective Disorder (SAD).
Depression can be treated in various ways. Counselling, psychotherapy, and antidepressant medicines may all be used. Lifestyle changes, such as getting more exercise, also may help.
Your doctor or mental health professional will help you find the best treatment. For severe depression, a very small number of people may need to stay in a hospital for a short time, especially if they are thinking about suicide.
Work with your health care team to find the best treatment for you. To get the most benefit, be sure you find a therapist who has experience treating people who have depression and who is trained in proven therapies, and use your medicines as your doctor directs.
If you don't get treated, depression may last from months to a year or longer. A small number of people feel depressed for most of their lives and always need treatment.
For more information, see the Therapy and Medications sections of this topic.
You can help yourself by getting support from family and friends, eating a balanced diet, avoiding alcohol, staying active, and getting enough sleep.
If you need help deciding whether to talk to your doctor about depression, see some common reasons people don't get help and how to overcome them.
For more information on making changes in your lifestyle to help with depression, see the Living With Depression section of this topic.
Other treatments for depression include electroconvulsive therapy (ECT) and alternative or complementary treatment. ECT involves an electric stimulation to the brain. Alternative treatments include the herb St. John's wort and omega-3 fatty acids. For more information on these treatments, see the Other Treatment section of this topic.
![]() One Man's Story: "...[T]his was the first time I was willing to do anything to recover. It's changed my whole life."—Stan |
There is little research on whether you can prevent a first bout of depression. But several studies suggest that exercise may help prevent a first bout of depression.2, 3 Exercise also may help prevent depression from coming back (relapse) and may improve symptoms of mild depression.2, 3
If you worry about getting depression, talk to your doctor. Regular screening for depression helps find depression early, and early treatment may help you get better faster.
You also may be able to prevent depression by avoiding alcohol and drugs. Alcohol and drugs can trigger depression. And using them is often a sign that you have depression.
You may be able to prevent a relapse or keep your symptoms from getting worse if you:
Counselling and psychotherapy are important parts of treatment for depression. You will work with a mental health professional such as a psychologist, mental health counsellor, clinical social worker, or psychiatrist. Together, you will develop an action plan to treat your depression.
The first step is finding a therapist you trust and feel comfortable with. The therapist also should have experience treating people who have depression and should be trained in proven therapies. These therapies include:5
Some therapists use acceptance and commitment therapy (ACT). In ACT, you work with a therapist to learn to accept your negative feelings but not let them run your life. You learn to make choices and act based on your personal values, not negative feelings.
Mindfulness strategies are another type of therapy. They seek to focus your attention on what is happening at the moment without trying to change it. These strategies teach you to let go of past regrets and not worry about the future. They may help with depression in some people.
Learn about:
Other treatments you may have heard of include problem-solving therapy, which looks at your current problems and helps you solve them, and family therapy, which brings you and your family together to discuss your relationships and depression. Experts don't know how well these therapies work for depression.5
When you hear "counselling" or "therapy," you may think of lying on a couch and talking about your childhood. But most of these treatments do not look for hidden memories. They deal with how you think about things and how you act each day.
![]() One Woman's Story: "I walked into the therapist's office crying, mute. I felt as if no one heard me." —Debbie |
How long your treatment lasts depends on how severe your depression is and how well you respond to treatment. Short-term counselling or therapy usually lasts from 10 to 20 weeks, and you usually see your mental health professional once a week. But you may need to meet with your health professional more often or for a longer time.
Antidepressant medicines may improve or completely relieve the symptoms of depression. If you are mildly depressed, you may not have to take them, but most people with moderate or severe depression need medicine.
Antidepressant medicines work in different ways. No antidepressant works better than another, but different ones work better or worse for different people. The side effects of antidepressant medicines are different and may lead you to choose one instead of another.
You may have to try different medicines or take more than one to help your symptoms. Most people find a medicine that works within a few tries. Other people take longer to find the right one and may need to take the antidepressant and another type of medicine, such as an antiseizure, mood stabilizer, antipsychotic, or antianxiety medicine.
Together you and your doctor will decide if you need medicine, what things you'll need to think about if you need medicine, and which medicine is right for you.
Antidepressant medicines include:
![]() One Woman's Story "It took about a year for me to not feel depressed at all."—Sherri |
If you take antidepressants, you should take them for at least 6 months after you begin to feel better. This can help prevent you from feeling depressed again (relapse). If this is not the first time you have been depressed, your doctor may want you to take these medicines even longer.
You may start to feel better within 1 to 3 weeks after starting your antidepressant medicine. But it can take as many as 6 to 8 weeks to see a great deal of improvement. If you have questions or concerns about your medicines, or if you do not notice that you feel better by 3 weeks, talk to your doctor.
Some people need to remain on medicine for several months to years. Others will need medicine long-term. This is more likely if you have had several bouts of depression that you had to treat in the hospital or that led you to attempt suicide.
Don't quit taking your medicines without talking to your doctor. If you quit suddenly, it can cause dizziness, anxiety, fatigue, and headache. If you and your doctor decide you can quit using medicine, gradually reduce the dose over several weeks.
Antidepressant medicines have side effects. You may notice the side effects before you notice that the medicine is helping you. Side effects vary depending on the medicine you take.
Antidepressant medicines have helped many people and are considered safe. But like all medicines, they may cause problems in certain people.
People who are taking medicines for other health problems need to know about medicine interactions. Talk with your doctor about the best way to track whether a combination of medicines is harming you. People who are taking a lot of medicines also are more likely to have harmful side effects.
When you're going through depression, you can't just shake if off. You might have a couple of good days followed by a bad day or a string of bad days. And you don't know how long it will last. Depression is not like the flu or a sprained ankle, where your doctor can tell you about how long it will take to get better.
When you're getting better, many experts call it recovery. Recovery is finding your path to the life you care about. There are 10 principles of recovery (What is a PDF document?) that can help you recover from depression on your terms. They help you gain self-confidence and respect for yourself.
During your recovery, be patient and kind to yourself. Remember that depression is not your fault and is not something you can overcome with willpower alone. You need treatment for depression, just like for any other illness.
Continuing your treatment, helping yourself, getting support, and having a healthy lifestyle are all part of your recovery. Your symptoms will fade as your treatment starts to work. Don't give up. Focus your energy on getting better. Your mood will improve. It just takes some time.
You can take many steps to help yourself when you feel depressed or are waiting for your medicine to work. These steps also help prevent depression from coming back.
You also can help yourself by thinking about what is good in your life. You can:
![]() One Woman's Story: "If you keep your thoughts in, they will never be quiet. It helps my depression to express them."—Cheryl |
Other treatments for depression include brain stimulation and treatment with herbs or dietary supplements.
Electroconvulsive therapy (ECT) may be used to treat severe depression or depression that does not get better with medicine and counselling or therapy. In ECT, electricity is briefly sent to the brain through electrodes placed on your head. Studies have shown that ECT is an effective short-term treatment for depression.3, 7
Other types of brain stimulation have not been well studied and may be expensive. They usually are considered only if other treatment does not work. They include:
Complementary therapies are sometimes used for depression. Always tell your doctor if you are using any of them.
If someone you care about is depressed, you may feel helpless. Maybe you're watching a once-active or happy person slide into inactivity or you're seeing a good friend lose interest in favourite activities. The change in your loved one's or friend's behaviour may be so big that you feel you no longer know him or her.
Here are some things you can do to help:
You can also help the person have good health habits. Encourage him or her to:
![]() One Woman's Story: "Having a friend or loved one to help you can really help."—Susan |
Depression can lead to suicide. Call 911 or check your local phone book or provincial website for resources on getting help in your area if the person:
Learn about depression and suicide and the warning signs of suicide, such as giving away things or suddenly using alcohol or drugs.
If a person or family member who is depressed talks about suicide and has a plan and a way to carry it out, follow these guidelines.
If you are spending a lot of time helping or caring for someone who has depression, find your own support. This can help you deal with the illness. These caregiver tips also can help you.
| Canadian Association for Suicide Prevention | |
| 870 Portage Avenue | |
| Winnipeg, MB R3G 0P1 | |
| Phone: | (204) 784-4073 |
| Fax: | (204) 772-7998 |
| Web Address: | www.suicideprevention.ca |
CASP’s purpose is to reduce the suicide rate and minimize the harmful consequences of suicidal behaviour. | |
| Canadian Mental Health Association | |
| 595 Montreal Road | |
| Suite 303 | |
| Ottawa, ON K1K 4L2 | |
| Fax: | (613) 745-5522 |
| Web Address: | www.cmha.ca |
The Canadian Mental Health Association (CMHA) promotes mental health and focuses on combatting mental health problems and emotional disorders. The organization offers workshops, pamphlets, newsletters, and other educational materials as well as contact information for local branches. | |
| Depression and Bipolar Support Alliance | |
| 730 North Franklin Street | |
| Suite 501 | |
| Chicago, IL 60654-7225 | |
| Phone: | 1-800-826-3632 includes a hotline for help with depression and bipolar disorder (312) 642-0049 |
| Fax: | (312) 642-7243 |
| Web Address: | www.dbsalliance.org |
The Depression and Bipolar Support Alliance publishes brochures, books, and videotapes about the treatment of mood disorders, all available free of charge or for a nominal fee. It also has an information and referral line, and its website contains helpful information. | |
| Mood Disorders Society of Canada | |
| 3-304 Stone Road West | |
| Suite 736 | |
| Guelph, ON N1G 4W4 | |
| Phone: | (519) 824-5565 |
| Fax: | (519) 824-9569 |
| Email: | info@mooddisorderscanada.ca |
| Web Address: | www.mooddisorderscanada.ca |
The Mood Disorders Society of Canada provides information, discussion forums, and support for patients and their families dealing with mental health problems such as depression and post traumatic stress disorder. | |
| Provincial Helplines and Websites | |
Many of the resources below provide help 24 hours a day, 7 days a week in multiple languages. In an emergency, call 911. Canada-wide resources
Alberta
British Columbia
New Brunswick
Ontario
Saskatchewan
Yukon
Other provinces Check your local phone book or provincial or territorial website. | |
Citations
- U.S. Preventive Services Task Force (2009). Screening for depression in adults: U.S. Preventive Services Task Force recommendation statement. Annals of Internal Medicine, 151(11): 784–792.
- Wiles NJ, et al. (2007). Physical activity and common mental disorders: Results from the Caerphilly study. American Journal of Epidemiology, 165(8): 946–954.
- Cipriani A, et al. (2011). Depression in adults (drug and other physical treatments), search date June 2009. BMJ Clinical Evidence. Available online: http://www.clinicalevidence.com.
- Paykel ES (2007). Cognitive therapy in relapse prevention in depression. International Journal of Neuropsychopharmacology, 10: 131–136.
- Butler R, et al. (2007). Depression in adults: Psychological treatments and care pathways, search date April 2006. Online version of BMJ Clinical Evidence (8). Available at: http://www.clinicalevidence.com.
- Buchner DM (2012). Physical activity. In L Goldman, A Shafer, eds., Cecil Medicine, 24th ed., pp. 56–58. Philadelphia: Saunders.
- UK ECT Review Group (2003). Efficacy and safety of electroconvulsive therapy in depressive disorders: A systematic review and meta-analysis. Lancet, 361(9360): 799–808.
Other Works Consulted
- American College of Obstetricians and Gynecologists (2008, reaffirmed 2009). Use of psychiatric medications during pregnancy and lactation. ACOG Practice Bulletin No. 92. Obstetrics and Gynecology, 111(4): 1001–1020.
- American Psychiatric Association (2010). Practice Guideline for the Treatment of Patients With Major Depressive Disorder, 3rd ed. Available online: http://psychiatryonline.org/guidelines.aspx.
- Baloch HA, Soares JC (2010). Mood disorders. In EG Nabel, ed., ACP Medicine, section 13, chap. 2. Hamilton, ON: BC Decker.
- Kennedy S, et al. (2009). Canadian Network for Mood and Anxiety Treatments (CANMAT) clinical guidelines for the management of major depressive disorder in adults. Journal of Affective Disorders, 117(Suppl 1): S1–S64.
- Lam RW, et al. (2004). Prescribing antidepressants for depression in 2005: Recent concerns and recommendations. Canadian Journal of Psychiatry, 49(12): 1–6 (insert). Also available online: http://publications.cpa-apc.org/media.php?mid=143.
- Matorin AA, Ruiz P (2009). Depression section of Clinical manifestations of psychiatric disorders. In BJ Sadock et al., eds., Kaplan and Sadock’s Comprehensive Textbook of Psychiatry, 9th ed., vol. 1, pp. 1094–1095. Philadelphia: Lippincott Williams and Wilkins.
- Murray MT, Bongiorno PB. (2006). Affective disorders. In JE Pizzorno Jr, MT Murray, eds. Textbook of Natural Medicine, 3rd ed., vol. 2, pp. 1427–1448. St. Louis: Churchill Livingstone Elsevier.
- Qaseem A, et al. (2008). Using second-generation antidepressants to treat depressive disorders: A clinical practice guideline from the American College of Physicians. Annals of Internal Medicine, 149(10): 725–733.
- Sadock BJ, Sadock VA (2007). Depression and bipolar disorder. In Kaplan and Sadock's Synopsis of Psychiatry, 10th ed., pp. 527-562. Philadelphia: Lippincott Williams and Wilkins.
- Safety of SSRI in pregnancy (2008). Medical Letter on Drugs and Therapeutics, 50(1299): 89–90.
| By | Healthwise Staff |
|---|---|
| Primary Medical Reviewer | Kathleen Romito, MD - Family Medicine |
| Primary Medical Reviewer | Brian D. O'Brien, MD - Internal Medicine |
| Specialist Medical Reviewer | Lisa S. Weinstock, MD - Psychiatry |
| Last Revised | June 12, 2012 |
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