What is Sjögren's syndrome?
Sjögren's syndrome (say "SHOH-grins") is a disease in which the immune system attacks the glands that make moisture for the body, such as tears and saliva . The damage keeps the glands from working the way they should and makes your eyes and mouth dry.
The disease may also cause other problems, such as fatigue and pain in the joints. In rare cases, it can damage the lungs, kidneys, and nerves.
Anyone can get Sjögren's, but it's most common in white women who are in their 40s and 50s.
What causes Sjögren's syndrome?
What are the symptoms?
The most common symptoms of Sjögren's syndrome are very dry eyes and mouth that last for at least 3 months and are not caused by medicines. You may have itching and burning in your eyes. Your mouth may feel very dry, as though it is full of cotton.
How is Sjögren's syndrome diagnosed?
Your doctor will do a physical examination and ask questions about your symptoms and past health. He or she will also ask about any medicines you're taking that could cause dry eyes and mouth. If needed, you may also have tests to:
- Measure tear flow.
- Measure saliva.
- Check for antibodies in your blood.
How is it treated?
Your treatment for Sjögren's syndrome will depend on how the disease affects you over time. In most cases, treatment will focus on helping you control your symptoms.
Using artificial teardrops, mouth lubricants, and saliva substitutes can help moisten your eyes, mouth, and throat. Your doctor may also prescribe medicines such as:
Stronger medicines may be recommended if these treatments do not control your symptoms.
There are also many things you can do at home to manage symptoms.
Frequently Asked Questions
Learning about Sjögren's syndrome:
Living with Sjögren's syndrome:
Other Places To Get Help
|American College of Rheumatology|
|2200 Lake Boulevard NE|
|Atlanta, GA 30319|
The American College of Rheumatology (ACR) and the Association of Rheumatology Health Professionals (ARHP, a division of ACR) are professional organizations of rheumatologists and associated health professionals who are dedicated to healing, preventing disability from, and curing the many types of arthritis and related disabling and sometimes fatal disorders of the joints, muscles, and bones. Members of the ACR are physicians; members of the ARHP include research scientists, nurses, physical and occupational therapists, psychologists, and social workers. Both the ACR and the ARHP provide professional education for their members.
The ACR website offers patient information fact sheets about rheumatic diseases, about medicines used to treat rheumatic diseases, and about care professionals.
|393 University Avenue|
|Toronto, ON M5G 1E6|
The Arthritis Society provides funding for arthritis research and offers information on patient care, public education, and self-management of arthritis.
|Canadian Ophthalmological Society|
|610-1525 Carling Avenue|
|Ottawa, ON K1Z 8R9|
The Canadian Ophthalmological Society is an association of eye doctors dedicated to helping the public take good care of their eyes and vision. This group provides educational information on eye conditions and diseases and eye safety.
|Sjögren's Syndrome Foundation|
|6707 Democracy Boulevard|
|Bethesda, MD 20817|
This nonprofit foundation educates both health professionals and people with Sjögren's syndrome about the disease. It also produces and distributes educational materials, including The Moisture Seekers newsletter, handbooks, videos, and medical articles. A network of chapters, support groups, and contacts organizes meetings, participates in health fairs, increases awareness in communities, and promotes local media campaigns. The foundation sponsors educational programs, symposia, and workshops, and advocates for research and treatment centers.
|U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health|
|1 AMS Circle|
|Bethesda, MD 20892-3675|
|Phone:||1-877-22-NIAMS (1-877-226-4267) toll-free|
The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is a governmental institute that serves the public and health professionals by providing information, locating other information sources, and participating in a national federal database of health information. NIAMS supports research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases and supports the training of scientists to carry out this research.
The NIAMS website provides health information referrals to the NIAMS Clearinghouse, which has information packages about diseases.
Other Works Consulted
- Jonsson R, et al. (2005). Sjögren's syndrome. In WJ Koopman, LW Moreland, eds., Arthritis and Allied Conditions: A Textbook of Rheumatology, 15th ed., vol. 2, pp. 1681–1705. Philadelphia: Lippincott Williams and Wilkins.
- Ramos-Casals M, et al. (2010). Treatment of primary Sjogren's syndrome. JAMA, 304(4): 452–460.
|Primary Medical Reviewer||Adam Husney, MD - Family Medicine|
|Specialist Medical Reviewer||E. Gregory Thompson, MD - Internal Medicine|
|Last Revised||June 13, 2012|
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