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HealthLink BC File #105, May 2010

Diphtheria, Tetanus, Pertussis, Hepatitis B, Polio, and Haemophilus Influenzae Type b
(DTaP-HB-IPV-Hib) Vaccine





Keep Your Child Safe

Immunization has saved more lives in Canada in the last 50 years than any other health measure.

What is the Infanrix-hexa™ (DTaP-HB-IPV-Hib) vaccine?

This vaccine protects against 6 diseases:

The vaccine is approved by Health Canada and is provided free as part of your child's routine immunizations. Call your public health nurse or doctor to make an appointment.

Who should get this vaccine?

Children between 2 months and 7 years of age who have not received any other vaccines containing DTaP should get Infanrix Hexa.

DTaP-IPV-Hib-HB Vaccine Child's Age at Vaccination
1st dose 2 months of age
2nd dose 4 months of age
3rd dose 6 months of age

The vaccine is given as a series of 3 doses or shots. The first dose is given at 2 months of age, the second at 4 months, and the third at 6 months of age. The vaccine is given at the same time as other childhood immunizations.

It is important to keep a record of all immunizations received.

Benefits of the vaccine

This vaccine is the best way to protect your child against diphtheria, tetanus, pertussis, hepatitis B, polio, and Haemophilus influenzae type b. These diseases can be serious and sometimes cause death. When you get your child vaccinated, you help protect others as well.

Possible reactions after the vaccine

Vaccines are very safe. It is much safer to get the vaccine than it is to get sick from one of these diseases.

Common reactions to the vaccine may include soreness, redness and swelling where the shot was given. Some may have a fever or experience crankiness, drowsiness, or a loss of appetite. These reactions are mild and generally last 1 to 2 days.

It is important to stay in the clinic for 15 minutes after getting any vaccine because there is an extremely rare possibility of a life-threatening allergic reaction called anaphylaxis. This may include hives, difficulty breathing, or swelling of the throat, tongue or lips. If this happens after you leave the clinic, call 911 or the local emergency number. This reaction can be treated, and occurs in fewer than one in a million people who get the vaccine.

Acetaminophen or Tylenol® can be given for fever or soreness. ASA or Aspirin® should NOT be given to anyone under 20 years of age due to the risk of Reye Syndrome.

Report serious or unexpected reactions to your public health nurse or doctor.

Who should not get this vaccine?

Speak with a public health nurse or doctor if your child has had a life-threatening reaction to a previous dose of diphtheria, tetanus, pertussis, hepatitis B, polio, or Haemophilus influenzae type b vaccine, or any component of the vaccine, including neomycin, polymyxin B or latex.

People who developed Guillain-Barré Syndrome (GBS) within 8 weeks of getting a tetanus vaccine should not get the DTaP-HB-IPV-Hib vaccine. GBS is a rare condition that can result in weakness and paralysis of the body's muscles.

The vaccine is not given to people 7 years of age and older.

What are diphtheria, tetanus, pertussis, Haemophilus influenzae type b, polio, and hepatitis B?

Diphtheria is a serious infection of the nose and throat. About 1 in 10 people who get diphtheria will die. The germ (bacteria) is spread through the air from person to person. The disease can result in very serious breathing problems. It can also cause heart failure and paralysis.

Pertussis, or "whooping cough," is a serious infection of the lungs and throat. About 1 in 2000 people who get pertussis will die. Pertussis can cause pneumonia, convulsions, brain damage or death. These complications are seen most often in infants. The germ (bacteria) is easily spread by coughing, sneezing or close face-to-face contact. Pertussis can cause severe coughing that often ends with a whooping sound before the next breath. This cough can last several months and occurs more often at night.

Tetanus, also called "lockjaw," is caused by a germ (bacteria) mostly found in the soil. When the bacteria enter the skin through a cut or scrape, they produce a poison that can cause painful tightening of muscles all over the body. It is very serious if the breathing muscles are affected. Up to 2 in 10 people who get tetanus will die.

Haemophilus influenzae type b(Hib) is a germ (bacteria) that most commonly infects children under 5 years old. It can cause serious and life-threatening infections including meningitis, an infection of the lining that covers the brain, and septicemia, an infection of the blood. For every 20 children who get sick, 1 will die. Hib infection is spread by coughing, sneezing, or close face-to-face contact.

Polio is a disease caused by infection with a virus. While some polio infections show no symptoms, others can result in paralysis of arms or legs and even death. Polio can be spread by contact with the bowel movements (stool) of an infected person. This can happen from eating food or drinking water contaminated with stool.

Hepatitis B is a virus that attacks the liver. It can cause serious disease including permanent liver damage called cirrhosis. Hepatitis B is also the main cause of liver cancer, which can be fatal. Hepatitis B virus is spread from one infected person to another by contact with blood or body fluids. Mothers who are infected with hepatitis B virus can pass the virus to their newborn babies during delivery. When young children get hepatitis B virus infection, they often do not have symptoms but most will stay infected for life. This is why protection with vaccine at a young age is important.


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